Learning deficit in cognitively normal APOE ε4 carriers with LOW β‐amyloid

Learning deficit in cognitively normal APOE ε4 carriers with LOW β‐amyloid

Abstract Introduction In cognitively normal (CN) adults, increased rates of amyloid beta (Aβ) accumulation can be detected in low Aβ (Aβ–) apolipoprotein E (APOE) ε4 carriers. We aimed to determine the effect of ε4 on the ability to benefit from experience (ie, learn) in Aβ– CNs. Methods Aβ– CNs (n ...

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Bibliographic Details
Main Authors: Yen Ying Lim, Jenalle E. Baker, Andrea Mills, Loren Bruns Jr, Christopher Fowler, Jurgen Fripp, Stephanie R. Rainey‐Smith, David Ames, Colin L Masters, Paul Maruff
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Alzheimer's disease
amyloid
apolipoprotein E
learning
memory
Online Access:https://doi.org/10.1002/dad2.12136

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