Classical and Counter-Regulatory Renin–Angiotensin System: Potential Key Roles in COVID-19 Pathophysiology

Classical and Counter-Regulatory Renin–Angiotensin System: Potential Key Roles in COVID-19 Pathophysiology

In the current COVID-19 pandemic, severe acute respiratory syndrome coronavirus 2 uses angiotensin-converting enzyme-2 (ACE-2) receptors for cell entry, leading to ACE-2 dysfunction and downregulation, which disturb the balance between the classical and counter-regulatory renin–angiotensin system (R...

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Bibliographic Details
Main Authors: Moudhi Almutlaq, MSc, Abir Abdullah Alamro, PhD, Fayhan Alroqi, MD, Tlili Barhoumi, PhD
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:CJC Open
Online Access:http://www.sciencedirect.com/science/article/pii/S2589790X21000998

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