History of periodontal treatment and risk for intrauterine growth restriction (IUGR)
Abstract Background To explore the hypothesis that maternal periodontitis is associated with increased risk for Intrauterine Growth Restriction (IUGR), we examined the risk of IUGR in relation to periodontal treatment before, during and after pregnancy. Methods We conducted a retrospective cohort an...
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| Format: | Article |
| Language: | English |
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BMC
2018-09-01
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| Series: | BMC Oral Health |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12903-018-0623-2 |
| _version_ | 1828284377782550528 |
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| author | Cande V. Ananth Howard F. Andrews Panos N. Papapanou Angela M. Ward Emilie Bruzelius Mary Lee Conicella David A. Albert |
| author_facet | Cande V. Ananth Howard F. Andrews Panos N. Papapanou Angela M. Ward Emilie Bruzelius Mary Lee Conicella David A. Albert |
| author_sort | Cande V. Ananth |
| collection | DOAJ |
| description | Abstract Background To explore the hypothesis that maternal periodontitis is associated with increased risk for Intrauterine Growth Restriction (IUGR), we examined the risk of IUGR in relation to periodontal treatment before, during and after pregnancy. Methods We conducted a retrospective cohort analysis of insurance claims data from 2009 to 2012 for women who delivered a singleton live birth (n = 32,168). IUGR was examined as a function of type and timing of dental treatment, adjusting for potential confounders in logistic regression. Sensitivity analysis evaluated the potential effects of unmeasured confounding. Results Women who received periodontal treatment after delivery, indicating the presence of untreated periodontal disease during pregnancy, had significantly higher odds of IUGR compared to women who received no periodontal treatment (adjusted OR 1.5, 95% CI 1.2, 1.8). Conclusions Periodontal treatment provided in the immediate postpartum period, a proxy for periodontitis during gestation, was associated with increased risk of IUGR. |
| first_indexed | 2024-04-13T09:00:48Z |
| format | Article |
| id | doaj.art-29e7178aafa04ccf9da3c9790a6ee3cc |
| institution | Directory Open Access Journal |
| issn | 1472-6831 |
| language | English |
| last_indexed | 2024-04-13T09:00:48Z |
| publishDate | 2018-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Oral Health |
| spelling | doaj.art-29e7178aafa04ccf9da3c9790a6ee3cc2022-12-22T02:53:08ZengBMCBMC Oral Health1472-68312018-09-011811810.1186/s12903-018-0623-2History of periodontal treatment and risk for intrauterine growth restriction (IUGR)Cande V. Ananth0Howard F. Andrews1Panos N. Papapanou2Angela M. Ward3Emilie Bruzelius4Mary Lee Conicella5David A. Albert6Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia UniversityDepartment of Biostatistics, Joseph L. Mailman School of Public Health, Columbia UniversityDivision of Periodontics, Section of Oral, Diagnostic and Rehabilitation Sciences, College of Dental Medicine, Columbia UniversitySection of Population Oral Health, College of Dental Medicine, Columbia UniversityDepartment of Epidemiology, Joseph L. Mailman School of Public Health, Columbia UniversityAetna Inc.Section of Population Oral Health, College of Dental Medicine, Columbia UniversityAbstract Background To explore the hypothesis that maternal periodontitis is associated with increased risk for Intrauterine Growth Restriction (IUGR), we examined the risk of IUGR in relation to periodontal treatment before, during and after pregnancy. Methods We conducted a retrospective cohort analysis of insurance claims data from 2009 to 2012 for women who delivered a singleton live birth (n = 32,168). IUGR was examined as a function of type and timing of dental treatment, adjusting for potential confounders in logistic regression. Sensitivity analysis evaluated the potential effects of unmeasured confounding. Results Women who received periodontal treatment after delivery, indicating the presence of untreated periodontal disease during pregnancy, had significantly higher odds of IUGR compared to women who received no periodontal treatment (adjusted OR 1.5, 95% CI 1.2, 1.8). Conclusions Periodontal treatment provided in the immediate postpartum period, a proxy for periodontitis during gestation, was associated with increased risk of IUGR.http://link.springer.com/article/10.1186/s12903-018-0623-2Periodontal treatmentFetal inflammatory responseIntrauterine growth restriction |
| spellingShingle | Cande V. Ananth Howard F. Andrews Panos N. Papapanou Angela M. Ward Emilie Bruzelius Mary Lee Conicella David A. Albert History of periodontal treatment and risk for intrauterine growth restriction (IUGR) BMC Oral Health Periodontal treatment Fetal inflammatory response Intrauterine growth restriction |
| title | History of periodontal treatment and risk for intrauterine growth restriction (IUGR) |
| title_full | History of periodontal treatment and risk for intrauterine growth restriction (IUGR) |
| title_fullStr | History of periodontal treatment and risk for intrauterine growth restriction (IUGR) |
| title_full_unstemmed | History of periodontal treatment and risk for intrauterine growth restriction (IUGR) |
| title_short | History of periodontal treatment and risk for intrauterine growth restriction (IUGR) |
| title_sort | history of periodontal treatment and risk for intrauterine growth restriction iugr |
| topic | Periodontal treatment Fetal inflammatory response Intrauterine growth restriction |
| url | http://link.springer.com/article/10.1186/s12903-018-0623-2 |
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