Effects of T-2 toxin on growth performance, feather quality, tibia development and blood parameters in Yangzhou goslings
ABSTRACT: T-2 toxin is a dangerous natural pollutant and widely exists in animal feed, often causing toxic damage to poultry, such as slow growth and development, immunosuppression, and death. Although geese are considered the most sensitive poultry to T-2 toxin, the exact damage caused by T-2 toxin...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-02-01
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| Series: | Poultry Science |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0032579122006769 |
| _version_ | 1811175464166752256 |
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| author | Wang Gu Qiang Bao Kaiqi Weng Jinlu Liu Shuwen Luo Jianzhou Chen Zheng Li Zhengfeng Cao Yu Zhang Yang Zhang Guohong Chen Qi Xu |
| author_facet | Wang Gu Qiang Bao Kaiqi Weng Jinlu Liu Shuwen Luo Jianzhou Chen Zheng Li Zhengfeng Cao Yu Zhang Yang Zhang Guohong Chen Qi Xu |
| author_sort | Wang Gu |
| collection | DOAJ |
| description | ABSTRACT: T-2 toxin is a dangerous natural pollutant and widely exists in animal feed, often causing toxic damage to poultry, such as slow growth and development, immunosuppression, and death. Although geese are considered the most sensitive poultry to T-2 toxin, the exact damage caused by T-2 toxin to geese is elusive. In the present study, a total of forty two 1-day-old healthy Yangzhou male goslings were randomly allotted seven diets contaminated with 0, 0.2, 0.4, 0.6, 0.8, 1.0, or 2.0 mg/kg T-2 toxin for 21 d, and the effects of T-2 toxin exposure on growth performance, feather quality, tibia development, and blood parameters were investigated. The results showed that T-2 toxin exposure significantly inhibited feed intake, body weight gain, shank length growth, and organ development (e.g., ileum, cecum, liver, spleen, bursa, and tibia) in a dose-dependent manner. In addition, the more serious feathering abnormalities and feather damage were observed in goslings exposed to a high dose of T-2 toxin (0.8, 1.0, and 2.0 mg/kg), which were mainly sparsely covered with short, dry, rough, curly, and gloss-free feathers on the back. We also found that hypertrophic chondrocytes of the tibial growth plate exhibited abnormal morphology and nuclear consolidation or loss, accompanied by necrosis and excessive apoptosis under 2.0 mg/kg T-2 toxin exposure. Moreover, 2.0 mg/kg T-2 toxin exposure triggered erythropenia, thrombocytosis, alanine aminotransferase, and aspartate aminotransferase activity, as well as high blood urea nitrogen, uric acid, and lactic dehydrogenase levels. Collectively, these data indicate that T-2 toxin had an adverse effect on the growth performance, feather quality, and tibia development, and caused liver and kidney damage and abnormal blood parameters in Yangzhou goslings, providing crucial information toward the prevention and control of T-2 toxin contamination in poultry feed. |
| first_indexed | 2024-04-10T19:37:25Z |
| format | Article |
| id | doaj.art-29e7d985d5aa457193c94445c495f3db |
| institution | Directory Open Access Journal |
| issn | 0032-5791 |
| language | English |
| last_indexed | 2024-04-10T19:37:25Z |
| publishDate | 2023-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Poultry Science |
| spelling | doaj.art-29e7d985d5aa457193c94445c495f3db2023-01-30T04:11:30ZengElsevierPoultry Science0032-57912023-02-011022102382Effects of T-2 toxin on growth performance, feather quality, tibia development and blood parameters in Yangzhou goslingsWang Gu0Qiang Bao1Kaiqi Weng2Jinlu Liu3Shuwen Luo4Jianzhou Chen5Zheng Li6Zhengfeng Cao7Yu Zhang8Yang Zhang9Guohong Chen10Qi Xu11College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu Province, 225009, PR ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu Province, 225009, PR ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu Province, 225009, PR ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu Province, 225009, PR ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu Province, 225009, PR ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu Province, 225009, PR ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu Province, 225009, PR ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu Province, 225009, PR ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu Province, 225009, PR ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu Province, 225009, PR ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu Province, 225009, PR China; Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu Province, 225009, PR China; Key Laboratory for Evaluation and Utilization of Livestock and Poultry Resources (Poultry), Ministry of Agriculture and Rural Affairs, PR ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu Province, 225009, PR China; Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu Province, 225009, PR China; Key Laboratory for Evaluation and Utilization of Livestock and Poultry Resources (Poultry), Ministry of Agriculture and Rural Affairs, PR China; Corresponding author:ABSTRACT: T-2 toxin is a dangerous natural pollutant and widely exists in animal feed, often causing toxic damage to poultry, such as slow growth and development, immunosuppression, and death. Although geese are considered the most sensitive poultry to T-2 toxin, the exact damage caused by T-2 toxin to geese is elusive. In the present study, a total of forty two 1-day-old healthy Yangzhou male goslings were randomly allotted seven diets contaminated with 0, 0.2, 0.4, 0.6, 0.8, 1.0, or 2.0 mg/kg T-2 toxin for 21 d, and the effects of T-2 toxin exposure on growth performance, feather quality, tibia development, and blood parameters were investigated. The results showed that T-2 toxin exposure significantly inhibited feed intake, body weight gain, shank length growth, and organ development (e.g., ileum, cecum, liver, spleen, bursa, and tibia) in a dose-dependent manner. In addition, the more serious feathering abnormalities and feather damage were observed in goslings exposed to a high dose of T-2 toxin (0.8, 1.0, and 2.0 mg/kg), which were mainly sparsely covered with short, dry, rough, curly, and gloss-free feathers on the back. We also found that hypertrophic chondrocytes of the tibial growth plate exhibited abnormal morphology and nuclear consolidation or loss, accompanied by necrosis and excessive apoptosis under 2.0 mg/kg T-2 toxin exposure. Moreover, 2.0 mg/kg T-2 toxin exposure triggered erythropenia, thrombocytosis, alanine aminotransferase, and aspartate aminotransferase activity, as well as high blood urea nitrogen, uric acid, and lactic dehydrogenase levels. Collectively, these data indicate that T-2 toxin had an adverse effect on the growth performance, feather quality, and tibia development, and caused liver and kidney damage and abnormal blood parameters in Yangzhou goslings, providing crucial information toward the prevention and control of T-2 toxin contamination in poultry feed.http://www.sciencedirect.com/science/article/pii/S0032579122006769T-2 toxingoslingsgrowth performancefeather qualitytibia development |
| spellingShingle | Wang Gu Qiang Bao Kaiqi Weng Jinlu Liu Shuwen Luo Jianzhou Chen Zheng Li Zhengfeng Cao Yu Zhang Yang Zhang Guohong Chen Qi Xu Effects of T-2 toxin on growth performance, feather quality, tibia development and blood parameters in Yangzhou goslings Poultry Science T-2 toxin goslings growth performance feather quality tibia development |
| title | Effects of T-2 toxin on growth performance, feather quality, tibia development and blood parameters in Yangzhou goslings |
| title_full | Effects of T-2 toxin on growth performance, feather quality, tibia development and blood parameters in Yangzhou goslings |
| title_fullStr | Effects of T-2 toxin on growth performance, feather quality, tibia development and blood parameters in Yangzhou goslings |
| title_full_unstemmed | Effects of T-2 toxin on growth performance, feather quality, tibia development and blood parameters in Yangzhou goslings |
| title_short | Effects of T-2 toxin on growth performance, feather quality, tibia development and blood parameters in Yangzhou goslings |
| title_sort | effects of t 2 toxin on growth performance feather quality tibia development and blood parameters in yangzhou goslings |
| topic | T-2 toxin goslings growth performance feather quality tibia development |
| url | http://www.sciencedirect.com/science/article/pii/S0032579122006769 |
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