Phycobiliproteins—A Family of Algae-Derived Biliproteins: Productions, Characterization and Pharmaceutical Potentials
Phycobiliproteins (PBPs) are colored and water-soluble biliproteins found in cyanobacteria, rhodophytes, cryptomonads and cyanelles. They are divided into three main types: allophycocyanin, phycocyanin and phycoerythrin, according to their spectral properties. There are two methods for PBPs preparat...
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| Format: | Article |
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MDPI AG
2022-07-01
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| Series: | Marine Drugs |
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| Online Access: | https://www.mdpi.com/1660-3397/20/7/450 |
| _version_ | 1797433376722911232 |
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| author | Huaxin Chen Hongtao Qi Peng Xiong |
| author_facet | Huaxin Chen Hongtao Qi Peng Xiong |
| author_sort | Huaxin Chen |
| collection | DOAJ |
| description | Phycobiliproteins (PBPs) are colored and water-soluble biliproteins found in cyanobacteria, rhodophytes, cryptomonads and cyanelles. They are divided into three main types: allophycocyanin, phycocyanin and phycoerythrin, according to their spectral properties. There are two methods for PBPs preparation. One is the extraction and purification of native PBPs from Cyanobacteria, Cryptophyta and Rhodophyta, and the other way is the production of recombinant PBPs by heterologous hosts. Apart from their function as light-harvesting antenna in photosynthesis, PBPs can be used as food colorants, nutraceuticals and fluorescent probes in immunofluorescence analysis. An increasing number of reports have revealed their pharmaceutical potentials such as antioxidant, anti-tumor, anti-inflammatory and antidiabetic effects. The advances in PBP biogenesis make it feasible to construct novel PBPs with various activities and produce recombinant PBPs by heterologous hosts at low cost. In this review, we present a critical overview on the productions, characterization and pharmaceutical potentials of PBPs, and discuss the key issues and future perspectives on the exploration of these valuable proteins. |
| first_indexed | 2024-03-09T10:15:10Z |
| format | Article |
| id | doaj.art-29ebba4f4a824c3e838236729003ea9b |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-03-09T10:15:10Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-29ebba4f4a824c3e838236729003ea9b2023-12-01T22:23:46ZengMDPI AGMarine Drugs1660-33972022-07-0120745010.3390/md20070450Phycobiliproteins—A Family of Algae-Derived Biliproteins: Productions, Characterization and Pharmaceutical PotentialsHuaxin Chen0Hongtao Qi1Peng Xiong2School of Life Sciences and Medicine, Shandong University of Technology, Zibo 255000, ChinaSchool of Life Sciences, Qingdao University, Qingdao 266000, ChinaSchool of Life Sciences and Medicine, Shandong University of Technology, Zibo 255000, ChinaPhycobiliproteins (PBPs) are colored and water-soluble biliproteins found in cyanobacteria, rhodophytes, cryptomonads and cyanelles. They are divided into three main types: allophycocyanin, phycocyanin and phycoerythrin, according to their spectral properties. There are two methods for PBPs preparation. One is the extraction and purification of native PBPs from Cyanobacteria, Cryptophyta and Rhodophyta, and the other way is the production of recombinant PBPs by heterologous hosts. Apart from their function as light-harvesting antenna in photosynthesis, PBPs can be used as food colorants, nutraceuticals and fluorescent probes in immunofluorescence analysis. An increasing number of reports have revealed their pharmaceutical potentials such as antioxidant, anti-tumor, anti-inflammatory and antidiabetic effects. The advances in PBP biogenesis make it feasible to construct novel PBPs with various activities and produce recombinant PBPs by heterologous hosts at low cost. In this review, we present a critical overview on the productions, characterization and pharmaceutical potentials of PBPs, and discuss the key issues and future perspectives on the exploration of these valuable proteins.https://www.mdpi.com/1660-3397/20/7/450phycobiliproteinphycobilinbiosynthesisalgaepharmaceutical potentials |
| spellingShingle | Huaxin Chen Hongtao Qi Peng Xiong Phycobiliproteins—A Family of Algae-Derived Biliproteins: Productions, Characterization and Pharmaceutical Potentials Marine Drugs phycobiliprotein phycobilin biosynthesis algae pharmaceutical potentials |
| title | Phycobiliproteins—A Family of Algae-Derived Biliproteins: Productions, Characterization and Pharmaceutical Potentials |
| title_full | Phycobiliproteins—A Family of Algae-Derived Biliproteins: Productions, Characterization and Pharmaceutical Potentials |
| title_fullStr | Phycobiliproteins—A Family of Algae-Derived Biliproteins: Productions, Characterization and Pharmaceutical Potentials |
| title_full_unstemmed | Phycobiliproteins—A Family of Algae-Derived Biliproteins: Productions, Characterization and Pharmaceutical Potentials |
| title_short | Phycobiliproteins—A Family of Algae-Derived Biliproteins: Productions, Characterization and Pharmaceutical Potentials |
| title_sort | phycobiliproteins a family of algae derived biliproteins productions characterization and pharmaceutical potentials |
| topic | phycobiliprotein phycobilin biosynthesis algae pharmaceutical potentials |
| url | https://www.mdpi.com/1660-3397/20/7/450 |
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