COMPARATIVE CHARACTERISTIC OF CRITERIA OF DIAGNOSTICS OF PRIMARY MYODYSTROPHY OF DAVIDENKO AND LANDOUZY-DEJERINE
Resume. Scapuloperoneal Davidenkovhs myodystrophy represents a fairly rare disease nowadays, which diagnosis is sometimes difficult. Scientists still continue to study the characteristics of the mutations that occur in human’s body within this disease. Biochemical and pathophysiological processes i...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Bogomolets National Medical University
2015-09-01
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| Series: | Ukrainian Scientific Medical Youth Journal |
| Subjects: | |
| Online Access: | https://mmj.nmuofficial.com/index.php/journal/article/view/228 |
| Summary: | Resume. Scapuloperoneal Davidenkovhs myodystrophy represents a fairly rare disease nowadays, which diagnosis is sometimes difficult. Scientists still continue to study the characteristics of the mutations that occur in human’s body within this disease. Biochemical and pathophysiological processes in the body of patients today have been studied too little.
The main problem, which concerns this article, is that the disease in its clinical course may look like Landouzy- Dejerine muscular dystrophy, which occurs much more frequently. The problem becomes more acute because there are controversies among scientists about the place of scapuloperoneal Davidenkovhs myodystrophy amongst others myodystrophies. Some scientists and scientific sources indicate that scapuloperoneal Davidenkovhs myodystrophy is one of the clinical forms of Landouzy- Dejerine muscular dystrophy or a very similar disease. But over the time, the scientists concluded that scapuloperoneal Davidenkovhs myodystrophy is an independent disease, as it has certain features in the clinical course. That is why this article is dedicated to the definition of the main clinical manifestations of scapuloperoneal Davidenkovhs myodystrophy as well as the identification of the main differences of this disease from Landouzy-Dejerine muscular dystrophy. The objects of the study were two families received in patient treatment in the neurological department of the Alexander Hospital: mother and her son, patients with Landouzy-Dejerine muscular dystrophy disease and mother with her daughter with scapuloperoneal Davidenkovhs myodystrophy disease. The results of objective and laboratory researches of these two families, their neurological status, medical history and treatment plan are presented in this article. The Analysis of the survey results of two families has once again shown that both myodystrophies in their clinical flow and development are very similar to each other. Both diseases inherited from the parents of the patients, hit the same muscle groups, are progressing rather slowly, and amenable to symptomatic treatment only. The article describes the clinical and laboratory criteria for differential diagnosis of scapuloperoneal Davidenkovhs myodystrophy and Landouzy-Dejerine muscular dystrophy. On example of clinical cases and also based on review of the medical scientific literature, the main differences between these two diseases are opend. Information on Davidenkovhs myodystrophy, as about an infrequent disease, is also provided separately. Criteria of diagnostics and feature of a clinical course of this disease are also given. |
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| ISSN: | 2786-6661 2786-667X |