First reported case of infective endocarditis caused by community-acquired methicillin-resistant Staphylococcus aureus not associated with healthcare contact in Brazil

We report here the first case of endocarditis due to CA-MRSA not associated with healthcare contact in Brazil in Brazil. A previously healthy patient presented with history of endocarditis following a traumatic wound infection. Patient had multiple positive blood cultures within 72 h of admission an...

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Bibliographic Details
Main Authors: Claudio Querido Fortes, Claudia Adelino Espanha, Flavio Pedreira Bustorff, Bruno Cordeiro Zappa, Adriana Lucia Pires Ferreira, Regina Barbosa Moreira, Nelson Gonçalves Pereira, Vance G. Fowler Jr., Hitesh Deshmukh
Format: Article
Language:English
Published: Elsevier
Series:Brazilian Journal of Infectious Diseases
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000600020&lng=en&tlng=en
Description
Summary:We report here the first case of endocarditis due to CA-MRSA not associated with healthcare contact in Brazil in Brazil. A previously healthy patient presented with history of endocarditis following a traumatic wound infection. Patient had multiple positive blood cultures within 72 h of admission and met modified Duke's criterion for infective endocarditis. The isolate was typed as Staphylococcal cassette chromosome (SCC) mec type IV and was positive for presence of Panton-Valentine leukocidin (PVL). Increased incidence of CA-MRSA endocarditis is a challenge for the internist to choose the best empirical therapy. Several authors have suggested an empirical therapy with both a beta-lactam and an anti-MRSA agent for serious S. aureus infections. Our patient was treated with Vancomycin and made complete recovery in 3 months.
ISSN:1678-4391