CCNG2 Overexpression Mediated by AKT Inhibits Tumor Cell Proliferation in Human Astrocytoma Cells

CCNG2 Overexpression Mediated by AKT Inhibits Tumor Cell Proliferation in Human Astrocytoma Cells

The cyclin family protein CCNG2 has an important inhibitory role in cancer initiation and progression, but the exact mechanism is still unknown. In this study, we examined the relationship between CCNG2 and the malignancy of astrocytomas and whether the AKT pathway, which is upregulated in astrocyto...

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Bibliographic Details
Main Authors: Danfeng Zhang, Chunhui Wang, Zhenxing Li, Yiming Li, Dawei Dai, Kaiwei Han, Liquan Lv, Yicheng Lu, Lijun Hou, Junyu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Neurology
Subjects:
astrocytoma
AKT pathway
carcinogenesis
CCNG2
MK 2206
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2018.00255/full

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