Overexpression of Toll-Like Receptor 4 Contributes to Phagocytosis of Salmonella Enterica Serovar Typhimurium via Phosphoinositide 3-Kinase Signaling in Sheep

Overexpression of Toll-Like Receptor 4 Contributes to Phagocytosis of Salmonella Enterica Serovar Typhimurium via Phosphoinositide 3-Kinase Signaling in Sheep

Background/Aims: Phagocytosis of bacteria by monocytes/macrophages can trigger the immune response and the clearance of bacteria. This innate immune response involves Toll-like receptor 4 (TLR4). However, much remains unknown about the mechanism of TLR4-regulated phagocytosis of Salmonella enterica...

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Bibliographic Details
Main Authors: Sutian Wang, Shoulong Deng, Yang Cao, Rui Zhang, Zhixian Wang, Xiaojing Jiang, Jiahao Wang, Xiaosheng Zhang, Jinlong Zhang, Guoshi Liu, Zhengxing  Lian
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Transgenic sheep
Toll-like receptor 4
Phagocytosis
PI3K
Scavenger receptor
Online Access:https://www.karger.com/Article/FullText/493032

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