Pathogenesis and clinical perspectives of extraintestinal manifestations in inflammatory bowel diseases

A considerable number of patients with inflammatory bowel disease (IBD) experience extraintestinal manifestations (EIMs), which can present either before or after IBD diagnosis. Unraveling the pathogenic pathways of EIMs in IBD is challenging because of the lack of reliable criteria for diagnosis an...

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Main Authors: Jung Min Kim, Jae Hee Cheon
Format: Article
Language:English
Published: Korean Association for the Study of Intestinal Diseases 2020-07-01
Series:Intestinal Research
Subjects:
Online Access:http://www.irjournal.org/upload/pdf/ir-2019-00128.pdf
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author Jung Min Kim
Jae Hee Cheon
author_facet Jung Min Kim
Jae Hee Cheon
author_sort Jung Min Kim
collection DOAJ
description A considerable number of patients with inflammatory bowel disease (IBD) experience extraintestinal manifestations (EIMs), which can present either before or after IBD diagnosis. Unraveling the pathogenic pathways of EIMs in IBD is challenging because of the lack of reliable criteria for diagnosis and difficulty in distinguishing EIMs from external pathologies caused by drugs or other etiologies. Optimizing treatment can also be difficult. Early diagnosis and management of EIM revolve around multidisciplinary teams, and they should have the resources necessary to make and implement appropriate decisions. In addition, specialists of the affected organs should be trained in IBD treatment. Furthermore, patient awareness regarding the extraintestinal symptoms of IBD is of paramount importance for improving patient understanding of disease and health outcomes. Herein, we review the pathogenesis and clinical perspectives of EIMs in IBD.
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spelling doaj.art-29f5b5ca6e284759a19dc61d35c7fe842022-12-22T00:04:55ZengKorean Association for the Study of Intestinal DiseasesIntestinal Research1598-91002288-19562020-07-0118324926410.5217/ir.2019.00128826Pathogenesis and clinical perspectives of extraintestinal manifestations in inflammatory bowel diseasesJung Min Kim0Jae Hee Cheon1 Department of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea Department of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, KoreaA considerable number of patients with inflammatory bowel disease (IBD) experience extraintestinal manifestations (EIMs), which can present either before or after IBD diagnosis. Unraveling the pathogenic pathways of EIMs in IBD is challenging because of the lack of reliable criteria for diagnosis and difficulty in distinguishing EIMs from external pathologies caused by drugs or other etiologies. Optimizing treatment can also be difficult. Early diagnosis and management of EIM revolve around multidisciplinary teams, and they should have the resources necessary to make and implement appropriate decisions. In addition, specialists of the affected organs should be trained in IBD treatment. Furthermore, patient awareness regarding the extraintestinal symptoms of IBD is of paramount importance for improving patient understanding of disease and health outcomes. Herein, we review the pathogenesis and clinical perspectives of EIMs in IBD.http://www.irjournal.org/upload/pdf/ir-2019-00128.pdfinflammatory bowel diseasesneuromuscular manifestationsskin manifestationseye manifestations
spellingShingle Jung Min Kim
Jae Hee Cheon
Pathogenesis and clinical perspectives of extraintestinal manifestations in inflammatory bowel diseases
Intestinal Research
inflammatory bowel diseases
neuromuscular manifestations
skin manifestations
eye manifestations
title Pathogenesis and clinical perspectives of extraintestinal manifestations in inflammatory bowel diseases
title_full Pathogenesis and clinical perspectives of extraintestinal manifestations in inflammatory bowel diseases
title_fullStr Pathogenesis and clinical perspectives of extraintestinal manifestations in inflammatory bowel diseases
title_full_unstemmed Pathogenesis and clinical perspectives of extraintestinal manifestations in inflammatory bowel diseases
title_short Pathogenesis and clinical perspectives of extraintestinal manifestations in inflammatory bowel diseases
title_sort pathogenesis and clinical perspectives of extraintestinal manifestations in inflammatory bowel diseases
topic inflammatory bowel diseases
neuromuscular manifestations
skin manifestations
eye manifestations
url http://www.irjournal.org/upload/pdf/ir-2019-00128.pdf
work_keys_str_mv AT jungminkim pathogenesisandclinicalperspectivesofextraintestinalmanifestationsininflammatoryboweldiseases
AT jaeheecheon pathogenesisandclinicalperspectivesofextraintestinalmanifestationsininflammatoryboweldiseases