Assessment of effectiveness of oral supplementation of isolated fiber of carrot on metabolic parameters in mature rats
The present study was conducted to evaluate the metabolic effects of isolated fiber of carrot supplementation in rats. Physicochemical properties of fiber were determined. The groups were as follows: animals fed a standard diet, control group; high fiber supplementation (70 mg); low fiber supplement...
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| Language: | English |
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Tsinghua University Press
2023-11-01
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| Series: | Food Science and Human Wellness |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S221345302300068X |
| _version_ | 1797697951928156160 |
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| author | Maria Rosana Ramirez Debora Manuale Juan Carlos Yori |
| author_facet | Maria Rosana Ramirez Debora Manuale Juan Carlos Yori |
| author_sort | Maria Rosana Ramirez |
| collection | DOAJ |
| description | The present study was conducted to evaluate the metabolic effects of isolated fiber of carrot supplementation in rats. Physicochemical properties of fiber were determined. The groups were as follows: animals fed a standard diet, control group; high fiber supplementation (70 mg); low fiber supplementation (35 mg); for 12 weeks. Blood samples were collected at the time of sacrifice. The weights of heart, liver, kidneys and spleen of the experimental rats with respect to body weight were recorded. Commercial kits were used to determine serum glucose concentration, lipid profile (cholesterol, HDL-cholesterol, triglycerides), and the two main aminotransferases glutamic-oxalacetic transaminase (GOT)/glutamate-pyruvate transaminase (GPT). A histopathological assay was performed on the heart, liver, and spleen tissues of animals. Supplementation with fiber favors weight loss in female ((242.03 ± 23.73)−(197.81 ± 10.45) g); and male rats ((262.50 ± 32.21)−(213.96 ± 12.56) g) and induces a decrease in glucose levels in the supplemented animals. With the exception of total high-density lipoprotein cholesterol, the other lipid fractions decrease significantly in rats supplemented. Fiber supplementation did not induce changes in the dissected organs of the supplemented animals. In conclusion supplementation of fiber, improves glucose control, lower plasma lipid concentrations and reduced body weight in normal rats. |
| first_indexed | 2024-03-12T03:47:14Z |
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| id | doaj.art-29f69e3f10654b8a86f5cc70b379f3cd |
| institution | Directory Open Access Journal |
| issn | 2213-4530 |
| language | English |
| last_indexed | 2024-03-12T03:47:14Z |
| publishDate | 2023-11-01 |
| publisher | Tsinghua University Press |
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| series | Food Science and Human Wellness |
| spelling | doaj.art-29f69e3f10654b8a86f5cc70b379f3cd2023-09-03T12:36:26ZengTsinghua University PressFood Science and Human Wellness2213-45302023-11-0112620222028Assessment of effectiveness of oral supplementation of isolated fiber of carrot on metabolic parameters in mature ratsMaria Rosana Ramirez0Debora Manuale1Juan Carlos Yori2Instituto Universitario de Ciencias de la Salud, Fundación Barceló, CONICET, Centeno 710, CP 3340, Santo Tome, Corrientes, Argentina; Consejo Nacional de Investigaciones Científicas Técnicas (CONICET), Buenos Aires C1033AAJ, Argentina; Corresponding author at: Instituto Universitario de Ciencias de la Salud, de la Fundación H.A. Barceló, Sede Santo Tome, Corrientes-Argentina, Centeno 710 (3340),Consejo Nacional de Investigaciones Científicas Técnicas (CONICET), Buenos Aires C1033AAJ, Argentina; Instituto de Investigaciones en Catálisis y Petroquímica (INCAPE) FIQ-UNL-CONICET, Parque Tecnológico Litoral Centro 3000, Santa Fe, Argentina; Facultad de Ingeniería Química, Universidad nacional del Litoral 3000, Santa Fe, ArgentinaConsejo Nacional de Investigaciones Científicas Técnicas (CONICET), Buenos Aires C1033AAJ, Argentina; Instituto de Investigaciones en Catálisis y Petroquímica (INCAPE) FIQ-UNL-CONICET, Parque Tecnológico Litoral Centro 3000, Santa Fe, Argentina; Facultad de Ingeniería Química, Universidad nacional del Litoral 3000, Santa Fe, ArgentinaThe present study was conducted to evaluate the metabolic effects of isolated fiber of carrot supplementation in rats. Physicochemical properties of fiber were determined. The groups were as follows: animals fed a standard diet, control group; high fiber supplementation (70 mg); low fiber supplementation (35 mg); for 12 weeks. Blood samples were collected at the time of sacrifice. The weights of heart, liver, kidneys and spleen of the experimental rats with respect to body weight were recorded. Commercial kits were used to determine serum glucose concentration, lipid profile (cholesterol, HDL-cholesterol, triglycerides), and the two main aminotransferases glutamic-oxalacetic transaminase (GOT)/glutamate-pyruvate transaminase (GPT). A histopathological assay was performed on the heart, liver, and spleen tissues of animals. Supplementation with fiber favors weight loss in female ((242.03 ± 23.73)−(197.81 ± 10.45) g); and male rats ((262.50 ± 32.21)−(213.96 ± 12.56) g) and induces a decrease in glucose levels in the supplemented animals. With the exception of total high-density lipoprotein cholesterol, the other lipid fractions decrease significantly in rats supplemented. Fiber supplementation did not induce changes in the dissected organs of the supplemented animals. In conclusion supplementation of fiber, improves glucose control, lower plasma lipid concentrations and reduced body weight in normal rats.http://www.sciencedirect.com/science/article/pii/S221345302300068XCarrot fiberOral supplementationAnimal studies |
| spellingShingle | Maria Rosana Ramirez Debora Manuale Juan Carlos Yori Assessment of effectiveness of oral supplementation of isolated fiber of carrot on metabolic parameters in mature rats Food Science and Human Wellness Carrot fiber Oral supplementation Animal studies |
| title | Assessment of effectiveness of oral supplementation of isolated fiber of carrot on metabolic parameters in mature rats |
| title_full | Assessment of effectiveness of oral supplementation of isolated fiber of carrot on metabolic parameters in mature rats |
| title_fullStr | Assessment of effectiveness of oral supplementation of isolated fiber of carrot on metabolic parameters in mature rats |
| title_full_unstemmed | Assessment of effectiveness of oral supplementation of isolated fiber of carrot on metabolic parameters in mature rats |
| title_short | Assessment of effectiveness of oral supplementation of isolated fiber of carrot on metabolic parameters in mature rats |
| title_sort | assessment of effectiveness of oral supplementation of isolated fiber of carrot on metabolic parameters in mature rats |
| topic | Carrot fiber Oral supplementation Animal studies |
| url | http://www.sciencedirect.com/science/article/pii/S221345302300068X |
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