Current Approaches in the Multimodal Management of Asthma in Adolescents—From Pharmacology to Personalized Therapy

Asthma and adolescence are two sensitive points and are difficult to manage when they coexist. The first is a chronic respiratory condition, with frequent onset in early childhood (between 3 and 5 years), which can improve or worsen with age. Adolescence is the period between childhood and adulthood...

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Main Authors: Vasile Valeriu Lupu, Elena Jechel, Silvia Fotea, Ionela Daniela Morariu, Iuliana Magdalena Starcea, Alice Azoicai, Adriana Mocanu, Elena Cristina Mitrofan, Ancuta Lupu, Dragos Munteanu, Minerva Codruta Badescu, Magdalena Cuciureanu, Ileana Ioniuc
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/11/9/2429
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author Vasile Valeriu Lupu
Elena Jechel
Silvia Fotea
Ionela Daniela Morariu
Iuliana Magdalena Starcea
Alice Azoicai
Adriana Mocanu
Elena Cristina Mitrofan
Ancuta Lupu
Dragos Munteanu
Minerva Codruta Badescu
Magdalena Cuciureanu
Ileana Ioniuc
author_facet Vasile Valeriu Lupu
Elena Jechel
Silvia Fotea
Ionela Daniela Morariu
Iuliana Magdalena Starcea
Alice Azoicai
Adriana Mocanu
Elena Cristina Mitrofan
Ancuta Lupu
Dragos Munteanu
Minerva Codruta Badescu
Magdalena Cuciureanu
Ileana Ioniuc
author_sort Vasile Valeriu Lupu
collection DOAJ
description Asthma and adolescence are two sensitive points and are difficult to manage when they coexist. The first is a chronic respiratory condition, with frequent onset in early childhood (between 3 and 5 years), which can improve or worsen with age. Adolescence is the period between childhood and adulthood (12–19 years), marked by various internal and external conflicts and a limited capacity to understand and accept any aspect that is delimited by the pattern of the social circle (of the entourage) frequented by the individual. Therefore, the clinician is faced with multiple attempts regarding the management of asthma encountered during the adolescent period, starting from the individualization of the therapy to the control of compliance (which depends equally on the adverse reactions, quality of life offered and support of the close circle) and the social integration of the subject, communication probably having a more important role in the monitoring and evolution of the condition than the preference for a certain therapeutic scheme. Current statistics draw attention to the increase in morbidity and mortality among children with bronchial asthma, an aspect demonstrated by the numerous hospitalizations recorded, due either to an escalation in the severity of this pathology or to faulty management. The purpose of this article is to review the delicate aspects in terms of controlling symptoms and maintaining a high quality of life among teenagers.
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spelling doaj.art-29f80d0171994f68867a66777d0a5e352023-11-19T09:41:11ZengMDPI AGBiomedicines2227-90592023-08-01119242910.3390/biomedicines11092429Current Approaches in the Multimodal Management of Asthma in Adolescents—From Pharmacology to Personalized TherapyVasile Valeriu Lupu0Elena Jechel1Silvia Fotea2Ionela Daniela Morariu3Iuliana Magdalena Starcea4Alice Azoicai5Adriana Mocanu6Elena Cristina Mitrofan7Ancuta Lupu8Dragos Munteanu9Minerva Codruta Badescu10Magdalena Cuciureanu11Ileana Ioniuc12Department of Pediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaDepartment of Pediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaClinical Medical Department, Faculty of Medicine and Pharmacy, “Dunarea de Jos” University of Galati, 800008 Galati, RomaniaFaculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaDepartment of Pediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaDepartment of Pediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaDepartment of Pediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaCF Clinical Hospital, 700506 Iasi, RomaniaDepartment of Pediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaFaculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaFaculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaDepartment of Pharmacology, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaDepartment of Pediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaAsthma and adolescence are two sensitive points and are difficult to manage when they coexist. The first is a chronic respiratory condition, with frequent onset in early childhood (between 3 and 5 years), which can improve or worsen with age. Adolescence is the period between childhood and adulthood (12–19 years), marked by various internal and external conflicts and a limited capacity to understand and accept any aspect that is delimited by the pattern of the social circle (of the entourage) frequented by the individual. Therefore, the clinician is faced with multiple attempts regarding the management of asthma encountered during the adolescent period, starting from the individualization of the therapy to the control of compliance (which depends equally on the adverse reactions, quality of life offered and support of the close circle) and the social integration of the subject, communication probably having a more important role in the monitoring and evolution of the condition than the preference for a certain therapeutic scheme. Current statistics draw attention to the increase in morbidity and mortality among children with bronchial asthma, an aspect demonstrated by the numerous hospitalizations recorded, due either to an escalation in the severity of this pathology or to faulty management. The purpose of this article is to review the delicate aspects in terms of controlling symptoms and maintaining a high quality of life among teenagers.https://www.mdpi.com/2227-9059/11/9/2429teenagerasthmaeosinophilsinterleukinmultimodal therapy
spellingShingle Vasile Valeriu Lupu
Elena Jechel
Silvia Fotea
Ionela Daniela Morariu
Iuliana Magdalena Starcea
Alice Azoicai
Adriana Mocanu
Elena Cristina Mitrofan
Ancuta Lupu
Dragos Munteanu
Minerva Codruta Badescu
Magdalena Cuciureanu
Ileana Ioniuc
Current Approaches in the Multimodal Management of Asthma in Adolescents—From Pharmacology to Personalized Therapy
Biomedicines
teenager
asthma
eosinophils
interleukin
multimodal therapy
title Current Approaches in the Multimodal Management of Asthma in Adolescents—From Pharmacology to Personalized Therapy
title_full Current Approaches in the Multimodal Management of Asthma in Adolescents—From Pharmacology to Personalized Therapy
title_fullStr Current Approaches in the Multimodal Management of Asthma in Adolescents—From Pharmacology to Personalized Therapy
title_full_unstemmed Current Approaches in the Multimodal Management of Asthma in Adolescents—From Pharmacology to Personalized Therapy
title_short Current Approaches in the Multimodal Management of Asthma in Adolescents—From Pharmacology to Personalized Therapy
title_sort current approaches in the multimodal management of asthma in adolescents from pharmacology to personalized therapy
topic teenager
asthma
eosinophils
interleukin
multimodal therapy
url https://www.mdpi.com/2227-9059/11/9/2429
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