Role of high-resolution sonography and doppler imaging in detecting nerve damage in leprosy patients

Leprosy is the chronic infectious disease-causing peripheral nerve damage leading to functional impairment of limbs, ulcer formation, and deformities. Pathological findings of leprosy are nerve enlargement and inflammation, with the help of high-resolution sonography and color Doppler (CD) imaging t...

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Main Authors: Joji Reddy Ontedddoo, N Bhavana, Gafoor J Abdul, B Suresh, M Padmalatha, D Harinath
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Journal of Dr. NTR University of Health Sciences
Subjects:
Online Access:http://www.jdrntruhs.org/article.asp?issn=2277-8632;year=2020;volume=9;issue=4;spage=230;epage=235;aulast=Ontedddoo
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author Joji Reddy Ontedddoo
N Bhavana
Gafoor J Abdul
B Suresh
M Padmalatha
D Harinath
author_facet Joji Reddy Ontedddoo
N Bhavana
Gafoor J Abdul
B Suresh
M Padmalatha
D Harinath
author_sort Joji Reddy Ontedddoo
collection DOAJ
description Leprosy is the chronic infectious disease-causing peripheral nerve damage leading to functional impairment of limbs, ulcer formation, and deformities. Pathological findings of leprosy are nerve enlargement and inflammation, with the help of high-resolution sonography and color Doppler (CD) imaging to demonstrate nerve enlargement and inflammation. Aims: To assess the role of high-resolution sonography in detecting nerve damage in leprosy patients. Methods and Materials: The study group of 30 cases of leprosy performed on e Soate My lab 40 and evaluated bilateral US of the ulnar (UN), lateral popliteal (LP), and posterior tibial (PT) nerves compared this with the sonographic findings in 30 healthy controls. Results and Conclusions: The nerves were significantly thicker in the leprosy patients as compared with healthy controls (P < 0.001 for each nerve). Increased neural vascularity was present in 47 of 158 examined nerves (3%). A significant correlation observed between clinical parameters of the grade of thickening, sensory loss and muscle weakness, and US abnormalities of nerve echotexture, endoneurial flow, and cross-sectional area. Studies have reported that clinical examination of enlarged nerves in leprosy patients is subjective and inaccurate, whereas ultrasonography (USG) provides an objective measure of nerve damage.
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spelling doaj.art-29f9abf5be37489abde9ab151cb18d0d2022-12-21T22:27:00ZengWolters Kluwer Medknow PublicationsJournal of Dr. NTR University of Health Sciences2277-86322020-01-019423023510.4103/JDRNTRUHS.JDRNTRUHS_123_19Role of high-resolution sonography and doppler imaging in detecting nerve damage in leprosy patientsJoji Reddy OntedddooN BhavanaGafoor J AbdulB SureshM PadmalathaD HarinathLeprosy is the chronic infectious disease-causing peripheral nerve damage leading to functional impairment of limbs, ulcer formation, and deformities. Pathological findings of leprosy are nerve enlargement and inflammation, with the help of high-resolution sonography and color Doppler (CD) imaging to demonstrate nerve enlargement and inflammation. Aims: To assess the role of high-resolution sonography in detecting nerve damage in leprosy patients. Methods and Materials: The study group of 30 cases of leprosy performed on e Soate My lab 40 and evaluated bilateral US of the ulnar (UN), lateral popliteal (LP), and posterior tibial (PT) nerves compared this with the sonographic findings in 30 healthy controls. Results and Conclusions: The nerves were significantly thicker in the leprosy patients as compared with healthy controls (P < 0.001 for each nerve). Increased neural vascularity was present in 47 of 158 examined nerves (3%). A significant correlation observed between clinical parameters of the grade of thickening, sensory loss and muscle weakness, and US abnormalities of nerve echotexture, endoneurial flow, and cross-sectional area. Studies have reported that clinical examination of enlarged nerves in leprosy patients is subjective and inaccurate, whereas ultrasonography (USG) provides an objective measure of nerve damage.http://www.jdrntruhs.org/article.asp?issn=2277-8632;year=2020;volume=9;issue=4;spage=230;epage=235;aulast=Ontedddoocolor dopplerhigh-resolution ultrasonographyleprosy
spellingShingle Joji Reddy Ontedddoo
N Bhavana
Gafoor J Abdul
B Suresh
M Padmalatha
D Harinath
Role of high-resolution sonography and doppler imaging in detecting nerve damage in leprosy patients
Journal of Dr. NTR University of Health Sciences
color doppler
high-resolution ultrasonography
leprosy
title Role of high-resolution sonography and doppler imaging in detecting nerve damage in leprosy patients
title_full Role of high-resolution sonography and doppler imaging in detecting nerve damage in leprosy patients
title_fullStr Role of high-resolution sonography and doppler imaging in detecting nerve damage in leprosy patients
title_full_unstemmed Role of high-resolution sonography and doppler imaging in detecting nerve damage in leprosy patients
title_short Role of high-resolution sonography and doppler imaging in detecting nerve damage in leprosy patients
title_sort role of high resolution sonography and doppler imaging in detecting nerve damage in leprosy patients
topic color doppler
high-resolution ultrasonography
leprosy
url http://www.jdrntruhs.org/article.asp?issn=2277-8632;year=2020;volume=9;issue=4;spage=230;epage=235;aulast=Ontedddoo
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