The Effect of Topical Dexamethasone on Postoperative Pain Intensity in Patients Undergoing Dacryocystorhinostomy Procedure
Background and Objective: It is very important and necessary to use certain methods in order to prevent or reduce the intensity of pain after surgery. Of all known methods, those that avoid the dangerous side effects of opioids or nonsteroidal anti-inflammatory drugs (NSAIDs) can be useful. The pres...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Babol University of Medical Sciences
2023-03-01
|
| Series: | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul |
| Subjects: | |
| Online Access: | http://jbums.org/article-1-10727-en.pdf |
| _version_ | 1797374895327281152 |
|---|---|
| author | S Jamali M Sabermoghaddam AA Sabermoghaddam MY Kiarudi E Bakhtiari |
| author_facet | S Jamali M Sabermoghaddam AA Sabermoghaddam MY Kiarudi E Bakhtiari |
| author_sort | S Jamali |
| collection | DOAJ |
| description | Background and Objective: It is very important and necessary to use certain methods in order to prevent or reduce the intensity of pain after surgery. Of all known methods, those that avoid the dangerous side effects of opioids or nonsteroidal anti-inflammatory drugs (NSAIDs) can be useful. The present study was conducted with the aim of investigating the effect of topical dexamethasone on postoperative pain intensity in patients undergoing dacryocystorhinostomy (DCR).
Methods: This double-blind randomized clinical trial was conducted on 80 patients aged 18-75 who were candidates for DCR and referred to Khatam Al-Anbia Hospital in Mashhad. Patients were randomly divided into control and intervention (dexamethasone) groups. In the intervention group, at the end of the procedure, a tampon impregnated with dexamethasone was placed in the upper part of the middle concha. In the control group, a tampon washed in distilled water was placed in the same place. Pain intensity was recorded on a verbal rating scale (VRS) 0, 3, 6, 12, 18 and 24 hours after the operation.
Findings: There was no significant difference in pain intensity at different time points in the two groups of intervention and control; the frequency of severe pain during recovery was equal to 22.5% and 15.7%, within 3 hours after the operation was equal to 17.5% and 10.0%, within 6 hours after the operation was equal to 12.5% and 0.5%, within 12 hours after the operation was equal to 12.5% and 2.5%, within 18 hours after the operation was equal to 0% and 2.5% and within 24 hours after the operation was equal to 0% and 0%, respectively. There was no significant difference in the process of changes in pain intensity during the 24 hours of the study based on the follow-up test.
Conclusion: The results of the study showed that topical use of a single dose of dexamethasone (8 mg) could not reduce postoperative pain as well as the need for opioids in DCR surgery. |
| first_indexed | 2024-03-08T19:12:22Z |
| format | Article |
| id | doaj.art-29fa1521bb324832999cfa0cc08fddcc |
| institution | Directory Open Access Journal |
| issn | 1561-4107 2251-7170 |
| language | English |
| last_indexed | 2024-03-08T19:12:22Z |
| publishDate | 2023-03-01 |
| publisher | Babol University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul |
| spelling | doaj.art-29fa1521bb324832999cfa0cc08fddcc2023-12-27T10:07:40ZengBabol University of Medical SciencesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul1561-41072251-71702023-03-012517887The Effect of Topical Dexamethasone on Postoperative Pain Intensity in Patients Undergoing Dacryocystorhinostomy ProcedureS Jamali0M Sabermoghaddam1AA Sabermoghaddam2MY Kiarudi3E Bakhtiari4 1.Eye Research Center, Mashhad University of Medical Sciences, Mashhad, I.R.Iran. 2.Department of Anesthesiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, I.R.Iran. 1.Eye Research Center, Mashhad University of Medical Sciences, Mashhad, I.R.Iran. 1.Eye Research Center, Mashhad University of Medical Sciences, Mashhad, I.R.Iran. 1.Eye Research Center, Mashhad University of Medical Sciences, Mashhad, I.R.Iran. Background and Objective: It is very important and necessary to use certain methods in order to prevent or reduce the intensity of pain after surgery. Of all known methods, those that avoid the dangerous side effects of opioids or nonsteroidal anti-inflammatory drugs (NSAIDs) can be useful. The present study was conducted with the aim of investigating the effect of topical dexamethasone on postoperative pain intensity in patients undergoing dacryocystorhinostomy (DCR). Methods: This double-blind randomized clinical trial was conducted on 80 patients aged 18-75 who were candidates for DCR and referred to Khatam Al-Anbia Hospital in Mashhad. Patients were randomly divided into control and intervention (dexamethasone) groups. In the intervention group, at the end of the procedure, a tampon impregnated with dexamethasone was placed in the upper part of the middle concha. In the control group, a tampon washed in distilled water was placed in the same place. Pain intensity was recorded on a verbal rating scale (VRS) 0, 3, 6, 12, 18 and 24 hours after the operation. Findings: There was no significant difference in pain intensity at different time points in the two groups of intervention and control; the frequency of severe pain during recovery was equal to 22.5% and 15.7%, within 3 hours after the operation was equal to 17.5% and 10.0%, within 6 hours after the operation was equal to 12.5% and 0.5%, within 12 hours after the operation was equal to 12.5% and 2.5%, within 18 hours after the operation was equal to 0% and 2.5% and within 24 hours after the operation was equal to 0% and 0%, respectively. There was no significant difference in the process of changes in pain intensity during the 24 hours of the study based on the follow-up test. Conclusion: The results of the study showed that topical use of a single dose of dexamethasone (8 mg) could not reduce postoperative pain as well as the need for opioids in DCR surgery.http://jbums.org/article-1-10727-en.pdfdacryocystorhinostomydexamethasonepainrandomized clinical trialverbal rating scale. |
| spellingShingle | S Jamali M Sabermoghaddam AA Sabermoghaddam MY Kiarudi E Bakhtiari The Effect of Topical Dexamethasone on Postoperative Pain Intensity in Patients Undergoing Dacryocystorhinostomy Procedure Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul dacryocystorhinostomy dexamethasone pain randomized clinical trial verbal rating scale. |
| title | The Effect of Topical Dexamethasone on Postoperative Pain Intensity in Patients Undergoing Dacryocystorhinostomy Procedure |
| title_full | The Effect of Topical Dexamethasone on Postoperative Pain Intensity in Patients Undergoing Dacryocystorhinostomy Procedure |
| title_fullStr | The Effect of Topical Dexamethasone on Postoperative Pain Intensity in Patients Undergoing Dacryocystorhinostomy Procedure |
| title_full_unstemmed | The Effect of Topical Dexamethasone on Postoperative Pain Intensity in Patients Undergoing Dacryocystorhinostomy Procedure |
| title_short | The Effect of Topical Dexamethasone on Postoperative Pain Intensity in Patients Undergoing Dacryocystorhinostomy Procedure |
| title_sort | effect of topical dexamethasone on postoperative pain intensity in patients undergoing dacryocystorhinostomy procedure |
| topic | dacryocystorhinostomy dexamethasone pain randomized clinical trial verbal rating scale. |
| url | http://jbums.org/article-1-10727-en.pdf |
| work_keys_str_mv | AT sjamali theeffectoftopicaldexamethasoneonpostoperativepainintensityinpatientsundergoingdacryocystorhinostomyprocedure AT msabermoghaddam theeffectoftopicaldexamethasoneonpostoperativepainintensityinpatientsundergoingdacryocystorhinostomyprocedure AT aasabermoghaddam theeffectoftopicaldexamethasoneonpostoperativepainintensityinpatientsundergoingdacryocystorhinostomyprocedure AT mykiarudi theeffectoftopicaldexamethasoneonpostoperativepainintensityinpatientsundergoingdacryocystorhinostomyprocedure AT ebakhtiari theeffectoftopicaldexamethasoneonpostoperativepainintensityinpatientsundergoingdacryocystorhinostomyprocedure AT sjamali effectoftopicaldexamethasoneonpostoperativepainintensityinpatientsundergoingdacryocystorhinostomyprocedure AT msabermoghaddam effectoftopicaldexamethasoneonpostoperativepainintensityinpatientsundergoingdacryocystorhinostomyprocedure AT aasabermoghaddam effectoftopicaldexamethasoneonpostoperativepainintensityinpatientsundergoingdacryocystorhinostomyprocedure AT mykiarudi effectoftopicaldexamethasoneonpostoperativepainintensityinpatientsundergoingdacryocystorhinostomyprocedure AT ebakhtiari effectoftopicaldexamethasoneonpostoperativepainintensityinpatientsundergoingdacryocystorhinostomyprocedure |