Hilly or mountainous surface: a new CT feature to predict the behavior of pure ground glass nodules?

Persistent pure ground-glass nodules (pGGNs) typically show an indolent course with very slow growth rates. These slow-growing lesions exhibit different growth patterns regardless of their initial computed tomography (CT) features. Therefore, predicting the aggressive behavior of pGGNs on initial CT...

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Main Authors: Andrea Borghesi, Silvia Michelini, Francesco Bertagna, Alessandra Scrimieri, Stefania Pezzotti, Roberto Maroldi
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:European Journal of Radiology Open
Online Access:http://www.sciencedirect.com/science/article/pii/S2352047718300522
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author Andrea Borghesi
Silvia Michelini
Francesco Bertagna
Alessandra Scrimieri
Stefania Pezzotti
Roberto Maroldi
author_facet Andrea Borghesi
Silvia Michelini
Francesco Bertagna
Alessandra Scrimieri
Stefania Pezzotti
Roberto Maroldi
author_sort Andrea Borghesi
collection DOAJ
description Persistent pure ground-glass nodules (pGGNs) typically show an indolent course with very slow growth rates. These slow-growing lesions exhibit different growth patterns regardless of their initial computed tomography (CT) features. Therefore, predicting the aggressive behavior of pGGNs on initial CT remains a diagnostic challenge. The literature reports that computerized analysis and various quantitative features have been tested to improve the risk stratification for pGGNs.The present article describes the long-term follow-up of two pGGNs with different behavior and introduces, for the first time, a new computerized method of analysis that could be helpful for predicting the future behavior of pGGNs. Keywords: Pure ground glass nodule, Multidetector computed tomography, Computer-assisted image analysis, Quantitative histogram analysis, Follow-up studies
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spelling doaj.art-29fc09eaf6504accad0e227549c548152022-12-22T02:01:43ZengElsevierEuropean Journal of Radiology Open2352-04772018-01-015177182Hilly or mountainous surface: a new CT feature to predict the behavior of pure ground glass nodules?Andrea Borghesi0Silvia Michelini1Francesco Bertagna2Alessandra Scrimieri3Stefania Pezzotti4Roberto Maroldi5Department of Radiology, University and Spedali Civili of Brescia, Brescia, Italy; Corresponding author at: Department of Radiology, University and Spedali Civili of Brescia; Piazzale Spedali Civili, 1, I - 25123 Brescia Italy.Department of Radiology, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, ItalyNuclear Medicine, University and Spedali Civili of Brescia, Brescia, ItalyDepartment of Radiology, University and Spedali Civili of Brescia, Brescia, ItalyDepartment of Radiology, University and Spedali Civili of Brescia, Brescia, ItalyDepartment of Radiology, University and Spedali Civili of Brescia, Brescia, ItalyPersistent pure ground-glass nodules (pGGNs) typically show an indolent course with very slow growth rates. These slow-growing lesions exhibit different growth patterns regardless of their initial computed tomography (CT) features. Therefore, predicting the aggressive behavior of pGGNs on initial CT remains a diagnostic challenge. The literature reports that computerized analysis and various quantitative features have been tested to improve the risk stratification for pGGNs.The present article describes the long-term follow-up of two pGGNs with different behavior and introduces, for the first time, a new computerized method of analysis that could be helpful for predicting the future behavior of pGGNs. Keywords: Pure ground glass nodule, Multidetector computed tomography, Computer-assisted image analysis, Quantitative histogram analysis, Follow-up studieshttp://www.sciencedirect.com/science/article/pii/S2352047718300522
spellingShingle Andrea Borghesi
Silvia Michelini
Francesco Bertagna
Alessandra Scrimieri
Stefania Pezzotti
Roberto Maroldi
Hilly or mountainous surface: a new CT feature to predict the behavior of pure ground glass nodules?
European Journal of Radiology Open
title Hilly or mountainous surface: a new CT feature to predict the behavior of pure ground glass nodules?
title_full Hilly or mountainous surface: a new CT feature to predict the behavior of pure ground glass nodules?
title_fullStr Hilly or mountainous surface: a new CT feature to predict the behavior of pure ground glass nodules?
title_full_unstemmed Hilly or mountainous surface: a new CT feature to predict the behavior of pure ground glass nodules?
title_short Hilly or mountainous surface: a new CT feature to predict the behavior of pure ground glass nodules?
title_sort hilly or mountainous surface a new ct feature to predict the behavior of pure ground glass nodules
url http://www.sciencedirect.com/science/article/pii/S2352047718300522
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