RECOMBINANT HUMAN LUTEINIZING HORMONE FOR THE TREATMENT OF INFERTILITY: THE GENERATION OF PRODUCER CELL LINES

RECOMBINANT HUMAN LUTEINIZING HORMONE FOR THE TREATMENT OF INFERTILITY: THE GENERATION OF PRODUCER CELL LINES

The aim of the study was to obtain the cell line secreting the maximum amounts of the human luteinizing hormone (LH) heterodimer without significant amounts of free LH alpha-subunit.Materials and methods. A pair of original plasmids of the p1.1 family containing long non coding segments of the Chine...

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Bibliographic Details
Main Authors:	N. A. Orlova, S. V. Kovnir, Yu. A. Khodak, M. A. Polzikov, I. I. Vorobiev
Format:	Article
Language:	Russian
Published:	IRBIS LLC 2017-12-01
Series:	Акушерство, гинекология и репродукция
Subjects:	luteinizing hormone chinese hamster ovary cells producer cell lines biopharmaceuticals biosimilar
Online Access:	https://www.gynecology.su/jour/article/view/425

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