Regulation of KV channel voltage-dependent activation by transmembrane β subunits

Regulation of KV channel voltage-dependent activation by transmembrane β subunits

Voltage-activated K+ (KV) channels are important for shaping action potentials and maintaining resting membrane potential in excitable cells. KV channels contain a central pore-gate domain (PGD) surrounded by four voltage-sensing domains (VSD). The VSDs will change conformation in response to altera...

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Bibliographic Details
Main Authors: Xiaohui eSun, Mark A. eZaydman, Jianmin eCui
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Pharmacology
Subjects:
BK
KCNQ1
Kv
channel
KCNE
KCNMB
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00063/full

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