Fibrolamellar Hepatocellular Carcinoma: Report of a Rare Case with Rapid Progression and Unusual Metastatic Sites
Fibrolamellar hepatocellular carcinoma (FLHCC) is a rare primary liver tumor that affects young adults, with unknown biology. We present a case of 21‐yr‐old female with a liver tumor revealed by hemangioma feature at first presentation, after few months, presented with metastatic liver cancer. In pa...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2021-04-01
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| Series: | Basic & Clinical Cancer Research |
| Subjects: | |
| Online Access: | https://bccr.tums.ac.ir/index.php/bccrj/article/view/330 |
| _version_ | 1818885201668866048 |
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| author | Adeleh Rezagholizadeh Shirvan Sarvazad Sotoudeh Mamak Tahmasebi |
| author_facet | Adeleh Rezagholizadeh Shirvan Sarvazad Sotoudeh Mamak Tahmasebi |
| author_sort | Adeleh Rezagholizadeh Shirvan |
| collection | DOAJ |
| description | Fibrolamellar hepatocellular carcinoma (FLHCC) is a rare primary liver tumor that affects young adults, with unknown biology. We present a case of 21‐yr‐old female with a liver tumor revealed by hemangioma feature at first presentation, after few months, presented with metastatic liver cancer. In pathologic investigation fibrolamellar hepatocellular carcinoma was confirmed. In spite of liver mass resection and lung metastasectomy, after short time, tumor recurrence was occurred. In 18F-FDG PET-CT scan ,lung, ovary, colon and peritoneal invasion was reported. Unfortunately, The patient died one year after diagnosis with rapid progression and multiple unusual metastatic site.
Here, we also review the literature concerning FLHCC in many aspects. |
| first_indexed | 2024-12-19T16:01:41Z |
| format | Article |
| id | doaj.art-29fed8b16e2e4d27a83d107356e92c08 |
| institution | Directory Open Access Journal |
| issn | 2228-6527 2228-5466 |
| language | English |
| last_indexed | 2024-12-19T16:01:41Z |
| publishDate | 2021-04-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Basic & Clinical Cancer Research |
| spelling | doaj.art-29fed8b16e2e4d27a83d107356e92c082022-12-21T20:14:55ZengTehran University of Medical SciencesBasic & Clinical Cancer Research2228-65272228-54662021-04-01124Fibrolamellar Hepatocellular Carcinoma: Report of a Rare Case with Rapid Progression and Unusual Metastatic SitesAdeleh Rezagholizadeh Shirvan0Sarvazad Sotoudeh1Mamak Tahmasebi2Palliative Medicine Unit, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, IranRadiation Oncology Research Center (RORC), Cancer Institute, Tehran University of Medical Sciences, Tehran, IranDepartment of Palliative Medicine, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, IranFibrolamellar hepatocellular carcinoma (FLHCC) is a rare primary liver tumor that affects young adults, with unknown biology. We present a case of 21‐yr‐old female with a liver tumor revealed by hemangioma feature at first presentation, after few months, presented with metastatic liver cancer. In pathologic investigation fibrolamellar hepatocellular carcinoma was confirmed. In spite of liver mass resection and lung metastasectomy, after short time, tumor recurrence was occurred. In 18F-FDG PET-CT scan ,lung, ovary, colon and peritoneal invasion was reported. Unfortunately, The patient died one year after diagnosis with rapid progression and multiple unusual metastatic site. Here, we also review the literature concerning FLHCC in many aspects.https://bccr.tums.ac.ir/index.php/bccrj/article/view/330Fibrolamellar Hepatocellular CarcinomaHCCMetastasis |
| spellingShingle | Adeleh Rezagholizadeh Shirvan Sarvazad Sotoudeh Mamak Tahmasebi Fibrolamellar Hepatocellular Carcinoma: Report of a Rare Case with Rapid Progression and Unusual Metastatic Sites Basic & Clinical Cancer Research Fibrolamellar Hepatocellular Carcinoma HCC Metastasis |
| title | Fibrolamellar Hepatocellular Carcinoma: Report of a Rare Case with Rapid Progression and Unusual Metastatic Sites |
| title_full | Fibrolamellar Hepatocellular Carcinoma: Report of a Rare Case with Rapid Progression and Unusual Metastatic Sites |
| title_fullStr | Fibrolamellar Hepatocellular Carcinoma: Report of a Rare Case with Rapid Progression and Unusual Metastatic Sites |
| title_full_unstemmed | Fibrolamellar Hepatocellular Carcinoma: Report of a Rare Case with Rapid Progression and Unusual Metastatic Sites |
| title_short | Fibrolamellar Hepatocellular Carcinoma: Report of a Rare Case with Rapid Progression and Unusual Metastatic Sites |
| title_sort | fibrolamellar hepatocellular carcinoma report of a rare case with rapid progression and unusual metastatic sites |
| topic | Fibrolamellar Hepatocellular Carcinoma HCC Metastasis |
| url | https://bccr.tums.ac.ir/index.php/bccrj/article/view/330 |
| work_keys_str_mv | AT adelehrezagholizadehshirvan fibrolamellarhepatocellularcarcinomareportofararecasewithrapidprogressionandunusualmetastaticsites AT sarvazadsotoudeh fibrolamellarhepatocellularcarcinomareportofararecasewithrapidprogressionandunusualmetastaticsites AT mamaktahmasebi fibrolamellarhepatocellularcarcinomareportofararecasewithrapidprogressionandunusualmetastaticsites |