Maternal Vitamin D Status and Children’s Asthma or Wheezing: A Narrative Review Article
Context: Asthma is a chronic inflammatory respiratory disorder, and nutritional conditions affect allergic diseases such as asthma. This study aims to find the relationship between maternal gestational vitamin D levels and asthma progression and wheezing in children later in life. Objectives: Aller...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2021-01-01
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| Series: | Journal of Pediatrics Review |
| Subjects: | |
| Online Access: | http://jpr.mazums.ac.ir/article-1-319-en.html |
| _version_ | 1818863989302493184 |
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| author | Zeinab Nazari Javad Ghaffari Abbas Dabaghzadeh Negar Ghaffari Ali Reza Ranjbar |
| author_facet | Zeinab Nazari Javad Ghaffari Abbas Dabaghzadeh Negar Ghaffari Ali Reza Ranjbar |
| author_sort | Zeinab Nazari |
| collection | DOAJ |
| description | Context: Asthma is a chronic inflammatory respiratory disorder, and nutritional conditions affect allergic diseases such as asthma. This study aims to find the relationship between maternal gestational vitamin D levels and asthma progression and wheezing in children later in life.
Objectives: Allergic disorders are common everywhere in the world. Asthma is the most chronic inflammatory respiratory disorder among children. It causes significant morbidity and mortality in children as well as adults. Vitamin D deficiency or insufficiency, is a global problem. Vitamin D has immunological effects, and it may prevent autoimmune diseases. Maternal plasma vitamin D during pregnancy has a different impact on children’s allergic disorders.
Evidence Acquisition: This is a review article. We searched databases, including Google Scholar, PubMed, SID, IranDoc, Scopus, until now. The keywords for the search included maternal vitamin D, asthma, wheezing, children, and pediatric. We searched in the mentioned databases until March 2020. Full-text articles in the English language were included in this study.
Results: A few articles were found in our search. All of them were cohort studies. They evaluated maternal vitamin D and its outcomes in their children’s asthma and wheezing using questionnaire data and serum samples. After assessing the articles (more than 100), 15 papers were included in our review. Six and four articles showed that higher maternal vitamin D levels reduce children’s asthma and or wheezing, respectively. In contrast, 7 articles showed no association between maternal vitamin D and children’s asthma or wheezing. Vitamin D does not have any serious side effects. Because the articles were heterogenic, a meta-analysis could not be done.
Conclusions: Administering vitamin D supplements or food enriched vitamin D during pregnancy has different effects on the prevalence of wheezing and or asthma in children. |
| first_indexed | 2024-12-19T10:24:31Z |
| format | Article |
| id | doaj.art-29ff1fd0899a469fa725e76fad9c3ca0 |
| institution | Directory Open Access Journal |
| issn | 2322-4398 2322-4401 |
| language | English |
| last_indexed | 2024-12-19T10:24:31Z |
| publishDate | 2021-01-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Pediatrics Review |
| spelling | doaj.art-29ff1fd0899a469fa725e76fad9c3ca02022-12-21T20:25:57ZengMazandaran University of Medical SciencesJournal of Pediatrics Review2322-43982322-44012021-01-019118Maternal Vitamin D Status and Children’s Asthma or Wheezing: A Narrative Review ArticleZeinab Nazari0Javad Ghaffari1Abbas Dabaghzadeh2Negar Ghaffari3Ali Reza Ranjbar4 Department of Gynecology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran. Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences. Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences. Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences. Institute of Interventional Allergology and Immunology, Cologne/Bonn, Germany. Context: Asthma is a chronic inflammatory respiratory disorder, and nutritional conditions affect allergic diseases such as asthma. This study aims to find the relationship between maternal gestational vitamin D levels and asthma progression and wheezing in children later in life. Objectives: Allergic disorders are common everywhere in the world. Asthma is the most chronic inflammatory respiratory disorder among children. It causes significant morbidity and mortality in children as well as adults. Vitamin D deficiency or insufficiency, is a global problem. Vitamin D has immunological effects, and it may prevent autoimmune diseases. Maternal plasma vitamin D during pregnancy has a different impact on children’s allergic disorders. Evidence Acquisition: This is a review article. We searched databases, including Google Scholar, PubMed, SID, IranDoc, Scopus, until now. The keywords for the search included maternal vitamin D, asthma, wheezing, children, and pediatric. We searched in the mentioned databases until March 2020. Full-text articles in the English language were included in this study. Results: A few articles were found in our search. All of them were cohort studies. They evaluated maternal vitamin D and its outcomes in their children’s asthma and wheezing using questionnaire data and serum samples. After assessing the articles (more than 100), 15 papers were included in our review. Six and four articles showed that higher maternal vitamin D levels reduce children’s asthma and or wheezing, respectively. In contrast, 7 articles showed no association between maternal vitamin D and children’s asthma or wheezing. Vitamin D does not have any serious side effects. Because the articles were heterogenic, a meta-analysis could not be done. Conclusions: Administering vitamin D supplements or food enriched vitamin D during pregnancy has different effects on the prevalence of wheezing and or asthma in children.http://jpr.mazums.ac.ir/article-1-319-en.htmlasthmachildrenvitamin dpregnancywheezing |
| spellingShingle | Zeinab Nazari Javad Ghaffari Abbas Dabaghzadeh Negar Ghaffari Ali Reza Ranjbar Maternal Vitamin D Status and Children’s Asthma or Wheezing: A Narrative Review Article Journal of Pediatrics Review asthma children vitamin d pregnancy wheezing |
| title | Maternal Vitamin D Status and Children’s Asthma or Wheezing: A Narrative Review Article |
| title_full | Maternal Vitamin D Status and Children’s Asthma or Wheezing: A Narrative Review Article |
| title_fullStr | Maternal Vitamin D Status and Children’s Asthma or Wheezing: A Narrative Review Article |
| title_full_unstemmed | Maternal Vitamin D Status and Children’s Asthma or Wheezing: A Narrative Review Article |
| title_short | Maternal Vitamin D Status and Children’s Asthma or Wheezing: A Narrative Review Article |
| title_sort | maternal vitamin d status and children s asthma or wheezing a narrative review article |
| topic | asthma children vitamin d pregnancy wheezing |
| url | http://jpr.mazums.ac.ir/article-1-319-en.html |
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