Ensemble structure description of Lys63-linked diubiquitin
The data described herein are related to the article entitled “Lys63-linked ubiquitin chain adopts multiple conformational states for specific target recognition” [1], and to the coordinates for the ensemble structure of Lys63-linked diubiquitin (PDB code 2N2K). A Lys63-linked diubiquitin exists in...
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| Format: | Article |
| Language: | English |
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Elsevier
2016-06-01
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| Series: | Data in Brief |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340916300257 |
| _version_ | 1828852617811329024 |
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| author | Zhu Liu Chun Tang |
| author_facet | Zhu Liu Chun Tang |
| author_sort | Zhu Liu |
| collection | DOAJ |
| description | The data described herein are related to the article entitled “Lys63-linked ubiquitin chain adopts multiple conformational states for specific target recognition” [1], and to the coordinates for the ensemble structure of Lys63-linked diubiquitin (PDB code 2N2K). A Lys63-linked diubiquitin exists in three conformational states with different orientations for the two subunits, each responsible for binding to a target protein and encoding a specific cell signal. An atomic entry in the ensemble structure file consists multiple lines, representing alternative locations of the atom and recapitulating the dynamics of the protein. Experimental details about obtaining strictly intramolecular paramagnetic restraints and determining the relative occupancies of the conformational states are presented. The experimental design and procedures in this Data article can be useful for characterizing the structure and dynamics of other multi-domain proteins. |
| first_indexed | 2024-12-12T23:57:06Z |
| format | Article |
| id | doaj.art-2a00d0df868e41088818357d7945c9ac |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-12-12T23:57:06Z |
| publishDate | 2016-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-2a00d0df868e41088818357d7945c9ac2022-12-22T00:06:32ZengElsevierData in Brief2352-34092016-06-0178188Ensemble structure description of Lys63-linked diubiquitinZhu Liu0Chun Tang1Key Laboratory of Magnetic Resonance in Biological Systems, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan, Hubei 430071, China; Zhejiang University School of Medicine, Hangzhou, Zhejiang Province 310028, ChinaKey Laboratory of Magnetic Resonance in Biological Systems, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan, Hubei 430071, China; Corresponding author.The data described herein are related to the article entitled “Lys63-linked ubiquitin chain adopts multiple conformational states for specific target recognition” [1], and to the coordinates for the ensemble structure of Lys63-linked diubiquitin (PDB code 2N2K). A Lys63-linked diubiquitin exists in three conformational states with different orientations for the two subunits, each responsible for binding to a target protein and encoding a specific cell signal. An atomic entry in the ensemble structure file consists multiple lines, representing alternative locations of the atom and recapitulating the dynamics of the protein. Experimental details about obtaining strictly intramolecular paramagnetic restraints and determining the relative occupancies of the conformational states are presented. The experimental design and procedures in this Data article can be useful for characterizing the structure and dynamics of other multi-domain proteins.http://www.sciencedirect.com/science/article/pii/S2352340916300257 |
| spellingShingle | Zhu Liu Chun Tang Ensemble structure description of Lys63-linked diubiquitin Data in Brief |
| title | Ensemble structure description of Lys63-linked diubiquitin |
| title_full | Ensemble structure description of Lys63-linked diubiquitin |
| title_fullStr | Ensemble structure description of Lys63-linked diubiquitin |
| title_full_unstemmed | Ensemble structure description of Lys63-linked diubiquitin |
| title_short | Ensemble structure description of Lys63-linked diubiquitin |
| title_sort | ensemble structure description of lys63 linked diubiquitin |
| url | http://www.sciencedirect.com/science/article/pii/S2352340916300257 |
| work_keys_str_mv | AT zhuliu ensemblestructuredescriptionoflys63linkeddiubiquitin AT chuntang ensemblestructuredescriptionoflys63linkeddiubiquitin |