Mixed bacterial-fungal infection following total hip arthroplasty: A case report
Prosthetic infection is one of the severe postoperative complications of arthroplasty. Mixed bacterial-fungal prosthetic infection is rare but can be disastrous. This case was a 76-year-old female suffered from prosthetic infection following total hip replacement due to femoral neck fracture and und...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-01-01
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| Series: | Chinese Journal of Traumatology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S100812752100122X |
| _version_ | 1818332414549688320 |
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| author | Yang-Jing Lin Tiao Su Liu Yang Guang-Xing Chen |
| author_facet | Yang-Jing Lin Tiao Su Liu Yang Guang-Xing Chen |
| author_sort | Yang-Jing Lin |
| collection | DOAJ |
| description | Prosthetic infection is one of the severe postoperative complications of arthroplasty. Mixed bacterial-fungal prosthetic infection is rare but can be disastrous. This case was a 76-year-old female suffered from prosthetic infection following total hip replacement due to femoral neck fracture and underwent multiple debridements. The culture of periprosthetic tissue was bacteriologically sterile following the first debridement, while the Staphylococcus hominis was identified in the second debridement in the previous hospitalization where fungal infection had not been considered. Thus the pathogen spectrum of anti-infection therapy failed to contain fungus. Ultimately, the culture result of our sampled periprosthetic tissue during the third debridement was Candida albicans without bacterium in our hospital. The fungal prosthetic infection was successfully treated by a two-stage revision with antifungal drugs. Accurate diagnosis and standardized treatment is the key to the therapy of infection after hip arthroplasty, especially for mixed bacterial-fungal prosthetic infection. |
| first_indexed | 2024-12-13T13:35:22Z |
| format | Article |
| id | doaj.art-2a0225eecb33463d8410a53ab8c739a7 |
| institution | Directory Open Access Journal |
| issn | 1008-1275 |
| language | English |
| last_indexed | 2024-12-13T13:35:22Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Chinese Journal of Traumatology |
| spelling | doaj.art-2a0225eecb33463d8410a53ab8c739a72022-12-21T23:43:53ZengElsevierChinese Journal of Traumatology1008-12752022-01-012513236Mixed bacterial-fungal infection following total hip arthroplasty: A case reportYang-Jing Lin0Tiao Su1Liu Yang2Guang-Xing Chen3Department of Joint Surgery, Southwest Hospital, Army Medical University, Chongqing 400038, ChinaDepartment of Joint Surgery, Southwest Hospital, Army Medical University, Chongqing 400038, ChinaDepartment of Joint Surgery, Southwest Hospital, Army Medical University, Chongqing 400038, ChinaCorresponding author.; Department of Joint Surgery, Southwest Hospital, Army Medical University, Chongqing 400038, ChinaProsthetic infection is one of the severe postoperative complications of arthroplasty. Mixed bacterial-fungal prosthetic infection is rare but can be disastrous. This case was a 76-year-old female suffered from prosthetic infection following total hip replacement due to femoral neck fracture and underwent multiple debridements. The culture of periprosthetic tissue was bacteriologically sterile following the first debridement, while the Staphylococcus hominis was identified in the second debridement in the previous hospitalization where fungal infection had not been considered. Thus the pathogen spectrum of anti-infection therapy failed to contain fungus. Ultimately, the culture result of our sampled periprosthetic tissue during the third debridement was Candida albicans without bacterium in our hospital. The fungal prosthetic infection was successfully treated by a two-stage revision with antifungal drugs. Accurate diagnosis and standardized treatment is the key to the therapy of infection after hip arthroplasty, especially for mixed bacterial-fungal prosthetic infection.http://www.sciencedirect.com/science/article/pii/S100812752100122XCandida albicansStaphylococcus hominisProsthesis-related infectionsArthroplastyHip |
| spellingShingle | Yang-Jing Lin Tiao Su Liu Yang Guang-Xing Chen Mixed bacterial-fungal infection following total hip arthroplasty: A case report Chinese Journal of Traumatology Candida albicans Staphylococcus hominis Prosthesis-related infections Arthroplasty Hip |
| title | Mixed bacterial-fungal infection following total hip arthroplasty: A case report |
| title_full | Mixed bacterial-fungal infection following total hip arthroplasty: A case report |
| title_fullStr | Mixed bacterial-fungal infection following total hip arthroplasty: A case report |
| title_full_unstemmed | Mixed bacterial-fungal infection following total hip arthroplasty: A case report |
| title_short | Mixed bacterial-fungal infection following total hip arthroplasty: A case report |
| title_sort | mixed bacterial fungal infection following total hip arthroplasty a case report |
| topic | Candida albicans Staphylococcus hominis Prosthesis-related infections Arthroplasty Hip |
| url | http://www.sciencedirect.com/science/article/pii/S100812752100122X |
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