Effectiveness of smoking cessation on the high-risk population of lung cancer with early screening: a systematic review and meta-analysis of randomized controlled trials until January 2022
Abstract Background Lung cancer has always been the malignant tumor with the highest incidence rate. Smoking is the most important risk factor for lung cancer. Although potential positive effects of smoking cessation interventions on the high-risk population of lung cancer have been observed, eviden...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-06-01
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| Series: | Archives of Public Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13690-023-01111-5 |
| _version_ | 1797811945197273088 |
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| author | Simin Huang Oufeng Tang Xutong Zheng Hui Li Yuxin Wu Liu Yang |
| author_facet | Simin Huang Oufeng Tang Xutong Zheng Hui Li Yuxin Wu Liu Yang |
| author_sort | Simin Huang |
| collection | DOAJ |
| description | Abstract Background Lung cancer has always been the malignant tumor with the highest incidence rate. Smoking is the most important risk factor for lung cancer. Although potential positive effects of smoking cessation interventions on the high-risk population of lung cancer have been observed, evidence of its definitive effect remains uncertain. This study aimed to summarize the evidence related to the effects and safety of smoking cessation interventions for the high-risk population of lung cancer. Methods A systematic literature search was conducted through the following seven databases: PubMed, Embase, Web of Science, CENTRAL, CINAHL, PsycINFO, and Science Direct. Screening and assessment for risk of bias were conducted by two independent reviewers. Meta-analysis was performed for the 7-day-point prevalence of smoking abstinence and continuous smoking abstinence using RevMan 5.3 software. Results Meta-analysis results show that in the 7-day-point prevalence of smoking abstinence (by patient-reported outcome): individualized intervention was significantly higher than that of the standard care [RR = 1.46, 95%CI = (1.04,2.06), P < 0.05]. Moreover, the smoking cessation interventions were significantly elevated than that of standard care [RR = 1.58, 95%CI = (1.12, 2.23), P < 0.05] within 1–6 month follow-up time. In line with the findings in cigarette smoking, the continuous smoking abstinence of E-cigarettes (biochemical verified): E-cigarettes were significantly higher than that of the standard care [RR = 1.51, 95%CI = (1.03, 2.21), P < 0.05], and within 1–6 month follow-up time, the smoking cessation interventions were significantly greater than that of standard care [RR = 1.51, 95%CI = (1.03, 2.21), P < 0.05]. Publication bias was detected possibly. Conclusions The results of this systematic review show that smoking cessation intervention is effective for long-term lung cancer high-risk smokers who participate in early screening, of which E-cigarettes are the best, followed by individual smoking cessation. Trial registration A review protocol was developed and registered in the International Prospective Register of Systematic Reviews (PROSPERO). Trial registration: CRD42019147151. Registered 23 June 2022. |
| first_indexed | 2024-03-13T07:30:15Z |
| format | Article |
| id | doaj.art-2a087d8fe01e4d1b89e35d8da3d03379 |
| institution | Directory Open Access Journal |
| issn | 2049-3258 |
| language | English |
| last_indexed | 2024-03-13T07:30:15Z |
| publishDate | 2023-06-01 |
| publisher | BMC |
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| series | Archives of Public Health |
| spelling | doaj.art-2a087d8fe01e4d1b89e35d8da3d033792023-06-04T11:07:09ZengBMCArchives of Public Health2049-32582023-06-0181111410.1186/s13690-023-01111-5Effectiveness of smoking cessation on the high-risk population of lung cancer with early screening: a systematic review and meta-analysis of randomized controlled trials until January 2022Simin Huang0Oufeng Tang1Xutong Zheng2Hui Li3Yuxin Wu4Liu Yang5School of Nursing, Fujian University of Traditional Chinese Medicine-FuzhouDepartment of Anesthesiology, West China Hospital of Sichuan University/West China School of Nursing, Sichuan University-ChengduSchool of Nursing, Fujian University of Traditional Chinese Medicine-FuzhouSchool of Nursing, Fujian University of Traditional Chinese Medicine-FuzhouJi’an College-Ji’anSchool of Nursing, Fujian University of Traditional Chinese Medicine-FuzhouAbstract Background Lung cancer has always been the malignant tumor with the highest incidence rate. Smoking is the most important risk factor for lung cancer. Although potential positive effects of smoking cessation interventions on the high-risk population of lung cancer have been observed, evidence of its definitive effect remains uncertain. This study aimed to summarize the evidence related to the effects and safety of smoking cessation interventions for the high-risk population of lung cancer. Methods A systematic literature search was conducted through the following seven databases: PubMed, Embase, Web of Science, CENTRAL, CINAHL, PsycINFO, and Science Direct. Screening and assessment for risk of bias were conducted by two independent reviewers. Meta-analysis was performed for the 7-day-point prevalence of smoking abstinence and continuous smoking abstinence using RevMan 5.3 software. Results Meta-analysis results show that in the 7-day-point prevalence of smoking abstinence (by patient-reported outcome): individualized intervention was significantly higher than that of the standard care [RR = 1.46, 95%CI = (1.04,2.06), P < 0.05]. Moreover, the smoking cessation interventions were significantly elevated than that of standard care [RR = 1.58, 95%CI = (1.12, 2.23), P < 0.05] within 1–6 month follow-up time. In line with the findings in cigarette smoking, the continuous smoking abstinence of E-cigarettes (biochemical verified): E-cigarettes were significantly higher than that of the standard care [RR = 1.51, 95%CI = (1.03, 2.21), P < 0.05], and within 1–6 month follow-up time, the smoking cessation interventions were significantly greater than that of standard care [RR = 1.51, 95%CI = (1.03, 2.21), P < 0.05]. Publication bias was detected possibly. Conclusions The results of this systematic review show that smoking cessation intervention is effective for long-term lung cancer high-risk smokers who participate in early screening, of which E-cigarettes are the best, followed by individual smoking cessation. Trial registration A review protocol was developed and registered in the International Prospective Register of Systematic Reviews (PROSPERO). Trial registration: CRD42019147151. Registered 23 June 2022.https://doi.org/10.1186/s13690-023-01111-5Early detection of cancerLung neoplasmsSmoking cessationSystematic reviewMeta-analysisRandomized controlled trial |
| spellingShingle | Simin Huang Oufeng Tang Xutong Zheng Hui Li Yuxin Wu Liu Yang Effectiveness of smoking cessation on the high-risk population of lung cancer with early screening: a systematic review and meta-analysis of randomized controlled trials until January 2022 Archives of Public Health Early detection of cancer Lung neoplasms Smoking cessation Systematic review Meta-analysis Randomized controlled trial |
| title | Effectiveness of smoking cessation on the high-risk population of lung cancer with early screening: a systematic review and meta-analysis of randomized controlled trials until January 2022 |
| title_full | Effectiveness of smoking cessation on the high-risk population of lung cancer with early screening: a systematic review and meta-analysis of randomized controlled trials until January 2022 |
| title_fullStr | Effectiveness of smoking cessation on the high-risk population of lung cancer with early screening: a systematic review and meta-analysis of randomized controlled trials until January 2022 |
| title_full_unstemmed | Effectiveness of smoking cessation on the high-risk population of lung cancer with early screening: a systematic review and meta-analysis of randomized controlled trials until January 2022 |
| title_short | Effectiveness of smoking cessation on the high-risk population of lung cancer with early screening: a systematic review and meta-analysis of randomized controlled trials until January 2022 |
| title_sort | effectiveness of smoking cessation on the high risk population of lung cancer with early screening a systematic review and meta analysis of randomized controlled trials until january 2022 |
| topic | Early detection of cancer Lung neoplasms Smoking cessation Systematic review Meta-analysis Randomized controlled trial |
| url | https://doi.org/10.1186/s13690-023-01111-5 |
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