Laminin-derived peptide, IKVAV, modulates macrophage phenotype through integrin mediation

Macrophages are highly plastic immune cells known to exist on a spectrum of phenotypes including pro-inflammatory (M1) or pro-healing (M2). Macrophages interact with extracellular matrix (ECM) ligands, such as fragments of collagen and laminin. Interaction of macrophages with ECM ligands is mediated...

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Bibliographic Details
Main Authors: Aakanksha Jha, Erika Moore
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Matrix Biology Plus
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590028524000036