Laminin-derived peptide, IKVAV, modulates macrophage phenotype through integrin mediation
Macrophages are highly plastic immune cells known to exist on a spectrum of phenotypes including pro-inflammatory (M1) or pro-healing (M2). Macrophages interact with extracellular matrix (ECM) ligands, such as fragments of collagen and laminin. Interaction of macrophages with ECM ligands is mediated...
Main Authors: | Aakanksha Jha, Erika Moore |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-06-01
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Series: | Matrix Biology Plus |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590028524000036 |
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