Prostate squamous cell carcinoma developing 11 years after external radiotherapy for prostate adenocarcinoma

Introduction Secondary bladder, colon, and rectal cancers are relatively common after prostate radiotherapy. However, secondary squamous cell carcinoma of the prostate is rare. Case presentation An 85‐year‐old man presented with dysuria and low‐serum prostate‐specific antigen levels. His medical his...

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Main Authors: Toru Matsugasumi, Hiroyuki Nakanishi, Tomohiro Yokota, Takumi Shiraishi, Osamu Ukimura
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:IJU Case Reports
Subjects:
Online Access:https://doi.org/10.1002/iju5.12161
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author Toru Matsugasumi
Hiroyuki Nakanishi
Tomohiro Yokota
Takumi Shiraishi
Osamu Ukimura
author_facet Toru Matsugasumi
Hiroyuki Nakanishi
Tomohiro Yokota
Takumi Shiraishi
Osamu Ukimura
author_sort Toru Matsugasumi
collection DOAJ
description Introduction Secondary bladder, colon, and rectal cancers are relatively common after prostate radiotherapy. However, secondary squamous cell carcinoma of the prostate is rare. Case presentation An 85‐year‐old man presented with dysuria and low‐serum prostate‐specific antigen levels. His medical history included localized prostate adenocarcinoma (Gleason score of 4 + 5) treated with combined three‐dimensional conformal radiotherapy and androgen deprivation therapy, 11 years ago. Urethroscopy and magnetic resonance imaging showed a bulging mass around the prostatic urethra. Transurethral resection of the prostate performed for histopathological diagnosis revealed squamous cell carcinoma. Conclusion Hereby, a rare case of secondary squamous cell carcinoma of the prostate after radiotherapy for adenocarcinoma was reported, which was found after 11 years of radiotherapy with symptom of dysuria including urinary hesitancy, difficulty, pain during urination, and low‐serum prostate‐specific antigen levels.
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spelling doaj.art-2a0c03c4318a4547856d7ee3121ef88f2022-12-21T20:34:20ZengWileyIJU Case Reports2577-171X2020-07-013412112410.1002/iju5.12161Prostate squamous cell carcinoma developing 11 years after external radiotherapy for prostate adenocarcinomaToru Matsugasumi0Hiroyuki Nakanishi1Tomohiro Yokota2Takumi Shiraishi3Osamu Ukimura4Department of Urology Kyoto Chubu Medical Center Nantan City Kyoto JapanDepartment of Urology Kyoto Chubu Medical Center Nantan City Kyoto JapanDepartment of Urology Kyoto Chubu Medical Center Nantan City Kyoto JapanDepartment of Urology Kyoto Prefectural University of Medicine Kyoto JapanDepartment of Urology Kyoto Prefectural University of Medicine Kyoto JapanIntroduction Secondary bladder, colon, and rectal cancers are relatively common after prostate radiotherapy. However, secondary squamous cell carcinoma of the prostate is rare. Case presentation An 85‐year‐old man presented with dysuria and low‐serum prostate‐specific antigen levels. His medical history included localized prostate adenocarcinoma (Gleason score of 4 + 5) treated with combined three‐dimensional conformal radiotherapy and androgen deprivation therapy, 11 years ago. Urethroscopy and magnetic resonance imaging showed a bulging mass around the prostatic urethra. Transurethral resection of the prostate performed for histopathological diagnosis revealed squamous cell carcinoma. Conclusion Hereby, a rare case of secondary squamous cell carcinoma of the prostate after radiotherapy for adenocarcinoma was reported, which was found after 11 years of radiotherapy with symptom of dysuria including urinary hesitancy, difficulty, pain during urination, and low‐serum prostate‐specific antigen levels.https://doi.org/10.1002/iju5.12161prostate‐specific antigenradiotherapysecondary prostate cancersquamous cell carcinoma
spellingShingle Toru Matsugasumi
Hiroyuki Nakanishi
Tomohiro Yokota
Takumi Shiraishi
Osamu Ukimura
Prostate squamous cell carcinoma developing 11 years after external radiotherapy for prostate adenocarcinoma
IJU Case Reports
prostate‐specific antigen
radiotherapy
secondary prostate cancer
squamous cell carcinoma
title Prostate squamous cell carcinoma developing 11 years after external radiotherapy for prostate adenocarcinoma
title_full Prostate squamous cell carcinoma developing 11 years after external radiotherapy for prostate adenocarcinoma
title_fullStr Prostate squamous cell carcinoma developing 11 years after external radiotherapy for prostate adenocarcinoma
title_full_unstemmed Prostate squamous cell carcinoma developing 11 years after external radiotherapy for prostate adenocarcinoma
title_short Prostate squamous cell carcinoma developing 11 years after external radiotherapy for prostate adenocarcinoma
title_sort prostate squamous cell carcinoma developing 11 years after external radiotherapy for prostate adenocarcinoma
topic prostate‐specific antigen
radiotherapy
secondary prostate cancer
squamous cell carcinoma
url https://doi.org/10.1002/iju5.12161
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AT tomohiroyokota prostatesquamouscellcarcinomadeveloping11yearsafterexternalradiotherapyforprostateadenocarcinoma
AT takumishiraishi prostatesquamouscellcarcinomadeveloping11yearsafterexternalradiotherapyforprostateadenocarcinoma
AT osamuukimura prostatesquamouscellcarcinomadeveloping11yearsafterexternalradiotherapyforprostateadenocarcinoma