Imaging of the Glucose-Dependent Insulinotropic Polypeptide Receptor Using a Novel Radiolabeled Peptide Rationally Designed Based on Endogenous GIP and Synthetic Exendin-4 Sequences

Imaging of the Glucose-Dependent Insulinotropic Polypeptide Receptor Using a Novel Radiolabeled Peptide Rationally Designed Based on Endogenous GIP and Synthetic Exendin-4 Sequences

Imaging and radiotherapy targeting the glucose-dependent insulinotropic polypeptide receptor (GIPR) could potentially benefit the management of neuroendocrine neoplasms (NENs), complementing clinically established radiopharmaceuticals. The aim of this study was to evaluate a GIPR-targeting positron...

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Bibliographic Details
Main Authors: Irina Velikyan, Martin Bossart, Torsten Haack, Iina Laitinen, Sergio Estrada, Lars Johansson, Stefan Pierrou, Michael Wagner, Olof Eriksson
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceuticals
Subjects:
GIPR
PET
insulinoma
neuroendocrine tumors
Online Access:https://www.mdpi.com/1424-8247/16/1/61

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