Changes in ventilatory mechanics caused by variations in PEEP and pressure support: study in healthy subjects under non-invasive mechanical ventilation
Introduction: Traditionally, ventilatory mechanics has been delivered in controlled modes through the use of inappropriate approaches for spontaneous ventilation. Objective: To measure the changes of ventilatory mechanics caused by PEEP and pressure support (PS) variations in non-invasive mechanical...
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| Format: | Article |
| Language: | English |
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Universidad Nacional de Colombia
2017-04-01
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| Series: | Revista de la Facultad de Medicina |
| Subjects: | |
| Online Access: | https://revistas.unal.edu.co/index.php/revfacmed/article/view/60938 |
| _version_ | 1811213537998012416 |
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| author | Isabel Cristina Muñoz Alher Mauricio Hernández |
| author_facet | Isabel Cristina Muñoz Alher Mauricio Hernández |
| author_sort | Isabel Cristina Muñoz |
| collection | DOAJ |
| description | Introduction: Traditionally, ventilatory mechanics has been delivered in controlled modes through the use of inappropriate approaches for spontaneous ventilation.
Objective: To measure the changes of ventilatory mechanics caused by PEEP and pressure support (PS) variations in non-invasive mechanical ventilation.
Materials and methods: The ventilatory mechanics was evaluated through a non-invasive strategy, under different PEEP and pressure support levels. For this purpose, a mechanical simulator was used, and a database of 14 healthy subjects non-invasively connected to a mechanical ventilator was recorded.
Results: For the 14 healthy subjects under PEEP and pressure support conditions of 0 cmH2O, the median resistance and compliance values were 91.2 [77.8-135.9] mL/cmH2O and 8.3[6.1-10.4]cmH2O/L/s, respectively. PEEP compliance showed a statistically significant increase in all subjects. On the other hand, no changes in any of the parameters were observed regarding pressure support increase.
Conclusions: The proposed technique allowed to find compliance and resistance values consistent with those set in the mechanical simulator, which, in turn, coincide with those reported in the literature for healthy subjects. This information is useful for decision-making in intensive care units.. |
| first_indexed | 2024-04-12T05:48:11Z |
| format | Article |
| id | doaj.art-2a0f2c4386994aa78716bafbdf5af196 |
| institution | Directory Open Access Journal |
| issn | 0120-0011 2357-3848 |
| language | English |
| last_indexed | 2024-04-12T05:48:11Z |
| publishDate | 2017-04-01 |
| publisher | Universidad Nacional de Colombia |
| record_format | Article |
| series | Revista de la Facultad de Medicina |
| spelling | doaj.art-2a0f2c4386994aa78716bafbdf5af1962022-12-22T03:45:22ZengUniversidad Nacional de ColombiaRevista de la Facultad de Medicina0120-00112357-38482017-04-0165232132810.15446/revfacmed.v65n2.6093846807Changes in ventilatory mechanics caused by variations in PEEP and pressure support: study in healthy subjects under non-invasive mechanical ventilationIsabel Cristina Muñoz0Alher Mauricio Hernández1Universidad de Antioquia - Facultad de Ingeniería - Grupo de Investigación en Bioinstrumentación e Ingeniería Clínica GIBIC - Medellín - Colombia.Universidad de Antioquia - Facultad de Ingeniería - Grupo de Investigación en Bioinstrumentación e Ingeniería Clínica GIBIC - Medellín - Colombia.Introduction: Traditionally, ventilatory mechanics has been delivered in controlled modes through the use of inappropriate approaches for spontaneous ventilation. Objective: To measure the changes of ventilatory mechanics caused by PEEP and pressure support (PS) variations in non-invasive mechanical ventilation. Materials and methods: The ventilatory mechanics was evaluated through a non-invasive strategy, under different PEEP and pressure support levels. For this purpose, a mechanical simulator was used, and a database of 14 healthy subjects non-invasively connected to a mechanical ventilator was recorded. Results: For the 14 healthy subjects under PEEP and pressure support conditions of 0 cmH2O, the median resistance and compliance values were 91.2 [77.8-135.9] mL/cmH2O and 8.3[6.1-10.4]cmH2O/L/s, respectively. PEEP compliance showed a statistically significant increase in all subjects. On the other hand, no changes in any of the parameters were observed regarding pressure support increase. Conclusions: The proposed technique allowed to find compliance and resistance values consistent with those set in the mechanical simulator, which, in turn, coincide with those reported in the literature for healthy subjects. This information is useful for decision-making in intensive care units..https://revistas.unal.edu.co/index.php/revfacmed/article/view/60938Ventilación no invasivaMecánica respiratoriaTrabajo respiratorio. |
| spellingShingle | Isabel Cristina Muñoz Alher Mauricio Hernández Changes in ventilatory mechanics caused by variations in PEEP and pressure support: study in healthy subjects under non-invasive mechanical ventilation Revista de la Facultad de Medicina Ventilación no invasiva Mecánica respiratoria Trabajo respiratorio. |
| title | Changes in ventilatory mechanics caused by variations in PEEP and pressure support: study in healthy subjects under non-invasive mechanical ventilation |
| title_full | Changes in ventilatory mechanics caused by variations in PEEP and pressure support: study in healthy subjects under non-invasive mechanical ventilation |
| title_fullStr | Changes in ventilatory mechanics caused by variations in PEEP and pressure support: study in healthy subjects under non-invasive mechanical ventilation |
| title_full_unstemmed | Changes in ventilatory mechanics caused by variations in PEEP and pressure support: study in healthy subjects under non-invasive mechanical ventilation |
| title_short | Changes in ventilatory mechanics caused by variations in PEEP and pressure support: study in healthy subjects under non-invasive mechanical ventilation |
| title_sort | changes in ventilatory mechanics caused by variations in peep and pressure support study in healthy subjects under non invasive mechanical ventilation |
| topic | Ventilación no invasiva Mecánica respiratoria Trabajo respiratorio. |
| url | https://revistas.unal.edu.co/index.php/revfacmed/article/view/60938 |
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