Curcumin/L‐OHP co‐loaded HAP for cGAS‐STING pathway activation to enhance the natural immune response in colorectal cancer

Curcumin/L‐OHP co‐loaded HAP for cGAS‐STING pathway activation to enhance the natural immune response in colorectal cancer

Abstract Insufficient immune cell infiltration into the tumor microenvironment (TME) greatly compromises the clinical application of immune‐checkpoint inhibitors (ICIs)‐based immunotherapy. Recent findings have shown that activation of the cyclic GMP‐AMP synthase‐stimulator of interferon genes (cGAS...

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Bibliographic Details
Main Authors: Yao Xiao, Guohu Guo, Huaiming Wang, Bin Peng, Yinglin Lin, Gaowen Qu, Ben Li, Zhaojun Jiang, Fan Zhang, Jiaming Wu, Min Liang
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Bioengineering & Translational Medicine
Subjects:
Ca2+ overload
cGAS/STING
innate immunity
mtDNA
nDNA
Online Access:https://doi.org/10.1002/btm2.10610

Internet

https://doi.org/10.1002/btm2.10610

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