Topical brimonidine induced acute uveal effusion in a patient with nanophthalmos: a case report

Abstract Background We report a case of uveal effusion in a nanophthalmic eye after topical use of brimonidine. Case presentation A 42-year-old male patient with nanophthalmos experienced sudden blurred vision in the right eye after using topical brimonidine when picking up tennis balls repeatedly 6...

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Main Authors: Yakun Li, Qi Zhou
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Ophthalmology
Subjects:
Online Access:https://doi.org/10.1186/s12886-023-03107-9
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author Yakun Li
Qi Zhou
author_facet Yakun Li
Qi Zhou
author_sort Yakun Li
collection DOAJ
description Abstract Background We report a case of uveal effusion in a nanophthalmic eye after topical use of brimonidine. Case presentation A 42-year-old male patient with nanophthalmos experienced sudden blurred vision in the right eye after using topical brimonidine when picking up tennis balls repeatedly 6 weeks after bilateral YAG peripheral iridotomy. Ocular examination showed wide choroidal and exudative retinal detachment in the temporal and inferior region, involving the macula. Acute uveal effusion in the right, bilateral nanophthalmos was diagnosed. Oral and topical corticosteroids, combined with topical nonsteroids and atropine led to a complete resolution of the uveal effusion after one month. Conclusion This case suggested a possible causal relationship between the topical use of brimonidine and acute uveal effusion in patients with nanophthalmos. Topical brimonidine should be used with caution in nanophthalmic eyes.
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spelling doaj.art-2a1c5998751f492b95c4cbf33b9f30342023-11-26T12:40:17ZengBMCBMC Ophthalmology1471-24152023-10-012311610.1186/s12886-023-03107-9Topical brimonidine induced acute uveal effusion in a patient with nanophthalmos: a case reportYakun Li0Qi Zhou1Department of Ophthalmology, Peking Union Medical College, Peking Union Medical College Hospital, Chinese Academy of Medical SciencesDepartment of Ophthalmology, Peking Union Medical College, Peking Union Medical College Hospital, Chinese Academy of Medical SciencesAbstract Background We report a case of uveal effusion in a nanophthalmic eye after topical use of brimonidine. Case presentation A 42-year-old male patient with nanophthalmos experienced sudden blurred vision in the right eye after using topical brimonidine when picking up tennis balls repeatedly 6 weeks after bilateral YAG peripheral iridotomy. Ocular examination showed wide choroidal and exudative retinal detachment in the temporal and inferior region, involving the macula. Acute uveal effusion in the right, bilateral nanophthalmos was diagnosed. Oral and topical corticosteroids, combined with topical nonsteroids and atropine led to a complete resolution of the uveal effusion after one month. Conclusion This case suggested a possible causal relationship between the topical use of brimonidine and acute uveal effusion in patients with nanophthalmos. Topical brimonidine should be used with caution in nanophthalmic eyes.https://doi.org/10.1186/s12886-023-03107-9Acute uveal effusionTopical brimonidineNanophthalmos
spellingShingle Yakun Li
Qi Zhou
Topical brimonidine induced acute uveal effusion in a patient with nanophthalmos: a case report
BMC Ophthalmology
Acute uveal effusion
Topical brimonidine
Nanophthalmos
title Topical brimonidine induced acute uveal effusion in a patient with nanophthalmos: a case report
title_full Topical brimonidine induced acute uveal effusion in a patient with nanophthalmos: a case report
title_fullStr Topical brimonidine induced acute uveal effusion in a patient with nanophthalmos: a case report
title_full_unstemmed Topical brimonidine induced acute uveal effusion in a patient with nanophthalmos: a case report
title_short Topical brimonidine induced acute uveal effusion in a patient with nanophthalmos: a case report
title_sort topical brimonidine induced acute uveal effusion in a patient with nanophthalmos a case report
topic Acute uveal effusion
Topical brimonidine
Nanophthalmos
url https://doi.org/10.1186/s12886-023-03107-9
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AT qizhou topicalbrimonidineinducedacuteuvealeffusioninapatientwithnanophthalmosacasereport