Pearl Kendrick, Grace Eldering, and the Pertussis Vaccine

In light of the reemergence of pertussis (whooping cough), the pioneering research of Pearl Kendrick and Grace Eldering is worth revisiting. In the 1930s, working in the Michigan Department of Health laboratory in Grand Rapids, Michigan, USA, they began researching a pertussis vaccine. Their researc...

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Main Author: Carolyn G. Shapiro-Shapin
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2010-08-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/16/8/10-0288_article
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author Carolyn G. Shapiro-Shapin
author_facet Carolyn G. Shapiro-Shapin
author_sort Carolyn G. Shapiro-Shapin
collection DOAJ
description In light of the reemergence of pertussis (whooping cough), the pioneering research of Pearl Kendrick and Grace Eldering is worth revisiting. In the 1930s, working in the Michigan Department of Health laboratory in Grand Rapids, Michigan, USA, they began researching a pertussis vaccine. Their research offers an instructive case study of the creative public health research performed in state health department laboratories during the interwar years. State department of health laboratory directors actively promoted research by supporting advanced education; making facilities and funding available for individual projects; and, when possible, procuring new facilities. Using Michigan Department of Health resources and local and federal funding, Kendrick and Eldering developed standardized diagnostic tools; modified and improved extant vaccines; conducted the first successful, large-scale, controlled clinical trial of pertussis vaccine; and participated in international efforts to standardize and disseminate the vaccine. Their model may again offer a promising avenue for groundbreaking research.
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spelling doaj.art-2a207efcf6e748ca942a8834728ddfad2022-12-22T02:06:00ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592010-08-011681273127810.3201/eid1608.100288Pearl Kendrick, Grace Eldering, and the Pertussis VaccineCarolyn G. Shapiro-ShapinIn light of the reemergence of pertussis (whooping cough), the pioneering research of Pearl Kendrick and Grace Eldering is worth revisiting. In the 1930s, working in the Michigan Department of Health laboratory in Grand Rapids, Michigan, USA, they began researching a pertussis vaccine. Their research offers an instructive case study of the creative public health research performed in state health department laboratories during the interwar years. State department of health laboratory directors actively promoted research by supporting advanced education; making facilities and funding available for individual projects; and, when possible, procuring new facilities. Using Michigan Department of Health resources and local and federal funding, Kendrick and Eldering developed standardized diagnostic tools; modified and improved extant vaccines; conducted the first successful, large-scale, controlled clinical trial of pertussis vaccine; and participated in international efforts to standardize and disseminate the vaccine. Their model may again offer a promising avenue for groundbreaking research.https://wwwnc.cdc.gov/eid/article/16/8/10-0288_articlePearl KendrickGrace Elderingpertussisstate departments of healthvaccineswhooping cough
spellingShingle Carolyn G. Shapiro-Shapin
Pearl Kendrick, Grace Eldering, and the Pertussis Vaccine
Emerging Infectious Diseases
Pearl Kendrick
Grace Eldering
pertussis
state departments of health
vaccines
whooping cough
title Pearl Kendrick, Grace Eldering, and the Pertussis Vaccine
title_full Pearl Kendrick, Grace Eldering, and the Pertussis Vaccine
title_fullStr Pearl Kendrick, Grace Eldering, and the Pertussis Vaccine
title_full_unstemmed Pearl Kendrick, Grace Eldering, and the Pertussis Vaccine
title_short Pearl Kendrick, Grace Eldering, and the Pertussis Vaccine
title_sort pearl kendrick grace eldering and the pertussis vaccine
topic Pearl Kendrick
Grace Eldering
pertussis
state departments of health
vaccines
whooping cough
url https://wwwnc.cdc.gov/eid/article/16/8/10-0288_article
work_keys_str_mv AT carolyngshapiroshapin pearlkendrickgraceelderingandthepertussisvaccine