Antihypertensive treatment in patients with end-stage renal disease
Arterial hypertension is a common finding in patients with end stage renal disease (80% patients are hypertensive). Cardiovascular diseases are the main cause of death in haemodialysis. The present study was performed to asses' successful treatment in hypertensive chronic haemodialysis patient...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2005-11-01
|
| Series: | Biomolecules & Biomedicine |
| Subjects: | |
| Online Access: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/3225 |
| _version_ | 1797260809925033984 |
|---|---|
| author | Mensura Aščerić Nedžad Mulabegović Sabina Nuhbegović Alma Nadarević Muamera Mujčinagić-Vrabac |
| author_facet | Mensura Aščerić Nedžad Mulabegović Sabina Nuhbegović Alma Nadarević Muamera Mujčinagić-Vrabac |
| author_sort | Mensura Aščerić |
| collection | DOAJ |
| description |
Arterial hypertension is a common finding in patients with end stage renal disease (80% patients are hypertensive). Cardiovascular diseases are the main cause of death in haemodialysis. The present study was performed to asses' successful treatment in hypertensive chronic haemodialysis patients by ultra filtration only and ultra filtration combined with medics. We studied 80 hypertensive adult patients who had been on regular haemodialysis treatment for at least 12 months (average duration of 41 months). All subjects were divided in two different antihypertensive treatment groups including 40 subjects each. The first group of patients were treated with trandolapril and ultra filtration, and the second group of patients were only treated with ultra filtration (control group). Blood pressure measurements before and after HD sessions were performed for each patient. Blood pressure control was defined using World Health Organizationcriteria 140/90 mm Hg. Average systolic blood pressure levels, after haemodialysis, were in the first group of patients 146.33 +/- 9.7 mm Hg, and in the control group 157,86 +/- 10.33 mm Hg. Average diastolic blood pressure was 87.83 +/- 8.11 mm Hg in the first group of patients and, in the control group it was 91.03 +/- 10.67 mm Hg. There were significant differences between systolic blood pressure level in the first group of patients and the control group of patients as well as in diastolic blood pressure (p < 0.05). We conclude that an antihypertensive therapy by trandolapril is more effective than ultra filtration alone in hypertensive patients on chronic haemodialysis.
|
| first_indexed | 2024-04-24T23:31:14Z |
| format | Article |
| id | doaj.art-2a26423268ff4041aa2005c4d31110cd |
| institution | Directory Open Access Journal |
| issn | 2831-0896 2831-090X |
| language | English |
| last_indexed | 2024-04-24T23:31:14Z |
| publishDate | 2005-11-01 |
| publisher | Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina |
| record_format | Article |
| series | Biomolecules & Biomedicine |
| spelling | doaj.art-2a26423268ff4041aa2005c4d31110cd2024-03-15T14:42:21ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2005-11-015410.17305/bjbms.2005.3225742Antihypertensive treatment in patients with end-stage renal diseaseMensura Aščerić0Nedžad Mulabegović1Sabina Nuhbegović2Alma Nadarević3Muamera Mujčinagić-Vrabac4Department of Pharmacology and Toxicology, University of Tuzla, Medical FacultyDepartment of Pharmacology and Toxicology, University of Sarajevo, Medical FacultyDepartment of Physiology, University of Tuzla, Medical FacultyPolyclinic for Pulmonary Diseases and TBC of Clinic of HealthFamily Practice of Clinic of Health Arterial hypertension is a common finding in patients with end stage renal disease (80% patients are hypertensive). Cardiovascular diseases are the main cause of death in haemodialysis. The present study was performed to asses' successful treatment in hypertensive chronic haemodialysis patients by ultra filtration only and ultra filtration combined with medics. We studied 80 hypertensive adult patients who had been on regular haemodialysis treatment for at least 12 months (average duration of 41 months). All subjects were divided in two different antihypertensive treatment groups including 40 subjects each. The first group of patients were treated with trandolapril and ultra filtration, and the second group of patients were only treated with ultra filtration (control group). Blood pressure measurements before and after HD sessions were performed for each patient. Blood pressure control was defined using World Health Organizationcriteria 140/90 mm Hg. Average systolic blood pressure levels, after haemodialysis, were in the first group of patients 146.33 +/- 9.7 mm Hg, and in the control group 157,86 +/- 10.33 mm Hg. Average diastolic blood pressure was 87.83 +/- 8.11 mm Hg in the first group of patients and, in the control group it was 91.03 +/- 10.67 mm Hg. There were significant differences between systolic blood pressure level in the first group of patients and the control group of patients as well as in diastolic blood pressure (p < 0.05). We conclude that an antihypertensive therapy by trandolapril is more effective than ultra filtration alone in hypertensive patients on chronic haemodialysis. https://www.bjbms.org/ojs/index.php/bjbms/article/view/3225Hypertensionhaemodialysisultra filtrationtrandolapril |
| spellingShingle | Mensura Aščerić Nedžad Mulabegović Sabina Nuhbegović Alma Nadarević Muamera Mujčinagić-Vrabac Antihypertensive treatment in patients with end-stage renal disease Biomolecules & Biomedicine Hypertension haemodialysis ultra filtration trandolapril |
| title | Antihypertensive treatment in patients with end-stage renal disease |
| title_full | Antihypertensive treatment in patients with end-stage renal disease |
| title_fullStr | Antihypertensive treatment in patients with end-stage renal disease |
| title_full_unstemmed | Antihypertensive treatment in patients with end-stage renal disease |
| title_short | Antihypertensive treatment in patients with end-stage renal disease |
| title_sort | antihypertensive treatment in patients with end stage renal disease |
| topic | Hypertension haemodialysis ultra filtration trandolapril |
| url | https://www.bjbms.org/ojs/index.php/bjbms/article/view/3225 |
| work_keys_str_mv | AT mensuraasceric antihypertensivetreatmentinpatientswithendstagerenaldisease AT nedzadmulabegovic antihypertensivetreatmentinpatientswithendstagerenaldisease AT sabinanuhbegovic antihypertensivetreatmentinpatientswithendstagerenaldisease AT almanadarevic antihypertensivetreatmentinpatientswithendstagerenaldisease AT muameramujcinagicvrabac antihypertensivetreatmentinpatientswithendstagerenaldisease |