The influence of modern living conditions on the human microbiome and potential therapeutic opportunities for allergy prevention
Modern living conditions and the recent surge in global urbanization have transformed the human microbiome. This transformation is believed to be a significant factor in the recent spike of common chronic inflammatory diseases like asthma and allergies worldwide, evident in both developed and develo...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | World Allergy Organization Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1939455123001175 |
| _version_ | 1797339133586178048 |
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| author | Guicheng Zhang, PhD Peter Le Souëf, MD, PhD |
| author_facet | Guicheng Zhang, PhD Peter Le Souëf, MD, PhD |
| author_sort | Guicheng Zhang, PhD |
| collection | DOAJ |
| description | Modern living conditions and the recent surge in global urbanization have transformed the human microbiome. This transformation is believed to be a significant factor in the recent spike of common chronic inflammatory diseases like asthma and allergies worldwide, evident in both developed and developing nations. Immigrants from less developed regions who settle in highly urbanized and affluent areas present an ideal demographic for research. Investigating immigrant populations can yield valuable insights, particularly when studying microbiome changes that occur as individuals transition from areas with low asthma prevalence to regions with a high prevalence of the condition. The application of prebiotics and probiotics as potential treatments for asthma and allergies faces challenges. This is due to the complex interplay of numerous factors that contribute to their aetiology. Exploring the interaction between the human microbiome and potential epigenetic changes in specific populations, such as immigrants adapting to new, urbanized environments, may offer crucial insights. Such research could underscore the role of prebiotics and probiotics in preventing allergic conditions. Recognizing the changes in the human microbiome in the context of a Western/modern environment might be essential in addressing the increasing prevalence of allergic diseases. Persistent research in this domain is pivotal for devising effective interventions such as dietary supplementation with prebiotics and probiotics. |
| first_indexed | 2024-03-08T09:41:31Z |
| format | Article |
| id | doaj.art-2a28430489134099826e9c6b409c9534 |
| institution | Directory Open Access Journal |
| issn | 1939-4551 |
| language | English |
| last_indexed | 2024-03-08T09:41:31Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | World Allergy Organization Journal |
| spelling | doaj.art-2a28430489134099826e9c6b409c95342024-01-30T04:14:23ZengElsevierWorld Allergy Organization Journal1939-45512024-01-01171100857The influence of modern living conditions on the human microbiome and potential therapeutic opportunities for allergy preventionGuicheng Zhang, PhD0Peter Le Souëf, MD, PhD1School of Population Health, Curtin University, Perth, 6102, Western Australia, Australia; School of Biomedical Sciences, The University of Western Australia, Perth, Western Australia 6008, Australia; Corresponding author.School of Population Health, Curtin University, Perth, 6102, Western Australia, Australia; School of Medicine, The University of Western Australia, Perth, Western Australia 6008, AustraliaModern living conditions and the recent surge in global urbanization have transformed the human microbiome. This transformation is believed to be a significant factor in the recent spike of common chronic inflammatory diseases like asthma and allergies worldwide, evident in both developed and developing nations. Immigrants from less developed regions who settle in highly urbanized and affluent areas present an ideal demographic for research. Investigating immigrant populations can yield valuable insights, particularly when studying microbiome changes that occur as individuals transition from areas with low asthma prevalence to regions with a high prevalence of the condition. The application of prebiotics and probiotics as potential treatments for asthma and allergies faces challenges. This is due to the complex interplay of numerous factors that contribute to their aetiology. Exploring the interaction between the human microbiome and potential epigenetic changes in specific populations, such as immigrants adapting to new, urbanized environments, may offer crucial insights. Such research could underscore the role of prebiotics and probiotics in preventing allergic conditions. Recognizing the changes in the human microbiome in the context of a Western/modern environment might be essential in addressing the increasing prevalence of allergic diseases. Persistent research in this domain is pivotal for devising effective interventions such as dietary supplementation with prebiotics and probiotics.http://www.sciencedirect.com/science/article/pii/S1939455123001175AsthmaAllergyMicrobiomeModern living conditionsImmigrants |
| spellingShingle | Guicheng Zhang, PhD Peter Le Souëf, MD, PhD The influence of modern living conditions on the human microbiome and potential therapeutic opportunities for allergy prevention World Allergy Organization Journal Asthma Allergy Microbiome Modern living conditions Immigrants |
| title | The influence of modern living conditions on the human microbiome and potential therapeutic opportunities for allergy prevention |
| title_full | The influence of modern living conditions on the human microbiome and potential therapeutic opportunities for allergy prevention |
| title_fullStr | The influence of modern living conditions on the human microbiome and potential therapeutic opportunities for allergy prevention |
| title_full_unstemmed | The influence of modern living conditions on the human microbiome and potential therapeutic opportunities for allergy prevention |
| title_short | The influence of modern living conditions on the human microbiome and potential therapeutic opportunities for allergy prevention |
| title_sort | influence of modern living conditions on the human microbiome and potential therapeutic opportunities for allergy prevention |
| topic | Asthma Allergy Microbiome Modern living conditions Immigrants |
| url | http://www.sciencedirect.com/science/article/pii/S1939455123001175 |
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