Anxiety and depression among cancer patients in Ethiopia: a systematic review and meta-analysis
IntroductionAnxiety and depression are among the common comorbidities of people diagnosed with cancer. However, despite the progress in therapeutic options and outcomes, mental health care and support have lagged behind for cancer patients. Estimating the extent and determinants of mental health dis...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-02-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1341448/full |
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| author | Habtamu Geremew Samuel Abdisa Elyas Melaku Mazengia Werkneh Melkie Tilahun Aysheshim Belaineh Haimanot Tigabu Kidie Tesfie Anteneh Lamesgen Mneneh Muluye Gebrie Mengie Bekalu Endalew Molla Yigzaw Birhanu Lakew Asmare Mulat Belay Simegn |
| author_facet | Habtamu Geremew Samuel Abdisa Elyas Melaku Mazengia Werkneh Melkie Tilahun Aysheshim Belaineh Haimanot Tigabu Kidie Tesfie Anteneh Lamesgen Mneneh Muluye Gebrie Mengie Bekalu Endalew Molla Yigzaw Birhanu Lakew Asmare Mulat Belay Simegn |
| author_sort | Habtamu Geremew |
| collection | DOAJ |
| description | IntroductionAnxiety and depression are among the common comorbidities of people diagnosed with cancer. However, despite the progress in therapeutic options and outcomes, mental health care and support have lagged behind for cancer patients. Estimating the extent and determinants of mental health disorders among cancer patients is crucial to alert concerned bodies for action. In view of this, we aimed to determine the pooled prevalence and determinants of anxiety and depression among cancer patients in Ethiopia.MethodsRelevant literatures were searched on PubMed, African Journals Online, Hinari, Epistemonikos, Scopus, EMBASE, CINAHL, Cochrane Library, and Gray literature sources. Data were extracted into an Excel spreadsheet and analyzed using STATA 17 statistical software. The random effect model was used to summarize the pooled effect sizes with their respective 95% confidence intervals. The I2 statistics and Egger’s regression test in conjunction with the funnel plot were utilized to evaluate heterogeneity and publication bias among included studies respectively.ResultsA total of 17 studies with 5,592 participants were considered in this review. The pooled prevalence of anxiety and depression among cancer patients in Ethiopia were 45.10% (95% CI: 36.74, 53.45) and 42.96% (95% CI: 34.98, 50.93), respectively. Primary and above education (OR= 0.76, 95% CI: 0.60, 0.97), poor social support (OR= 2.27, 95% CI: 1.29, 3.98), occupational status (OR= 0.59; 95% CI: 0.43, 0.82), advanced cancer stage (OR= 2.19, 95% CI: 1.38, 3.47), comorbid illness (OR= 1.67; 95% CI: 1.09, 2.58) and poor sleep quality (OR= 11.34, 95% CI: 6.47, 19.89) were significantly associated with depression. Whereas, advanced cancer stage (OR= 1.59, 95% CI: 1.15, 2.20) and poor sleep quality (OR= 12.56, 95% CI: 6.4 1, 24.62) were the factors associated with anxiety.ConclusionThis meta-analysis indicated that a substantial proportion of cancer patients suffer from anxiety and depression in Ethiopia. Educational status, occupational status, social support, cancer stage, comorbid illness and sleep quality were significantly associated with depression. Whereas, anxiety was predicted by cancer stage and sleep quality. Thus, the provision of comprehensive mental health support as a constituent of chronic cancer care is crucial to mitigate the impact and occurrence of anxiety and depression among cancer patients. Besides, families and the community should strengthen social support for cancer patients.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42023468621. |
| first_indexed | 2024-03-07T23:04:53Z |
| format | Article |
| id | doaj.art-2a29243628844d04b0934c9e94cc597f |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-03-07T23:04:53Z |
| publishDate | 2024-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-2a29243628844d04b0934c9e94cc597f2024-02-22T04:54:43ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402024-02-011510.3389/fpsyt.2024.13414481341448Anxiety and depression among cancer patients in Ethiopia: a systematic review and meta-analysisHabtamu Geremew0Samuel Abdisa1Elyas Melaku Mazengia2Werkneh Melkie Tilahun3Aysheshim Belaineh Haimanot4Tigabu Kidie Tesfie5Anteneh Lamesgen Mneneh6Muluye Gebrie Mengie7Bekalu Endalew8Molla Yigzaw Birhanu9Lakew Asmare10Mulat Belay Simegn11College of Health Science, Oda Bultum University, Chiro, EthiopiaDepartment of Midwifery, College of Health Science, Oda Bultum University, Chiro, EthiopiaDepartment of Public Health, College of Medicine and Health Science, Debre Markos University, Debre Markos, EthiopiaDepartment of Public Health, College of Medicine and Health Science, Debre Markos University, Debre Markos, EthiopiaDepartment of Public Health, College of Medicine and Health Science, Debre Markos University, Debre Markos, EthiopiaDepartment of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaDepartment of Public Health, College of Medicine and Health Science, Debre Markos University, Debre Markos, EthiopiaDepartment of Public Health, College of Medicine and Health Science, Debre Markos University, Debre Markos, EthiopiaDepartment of Public Health, College of Medicine and Health Science, Debre Markos University, Debre Markos, EthiopiaDepartment of Public Health, College of Medicine and Health Science, Debre Markos University, Debre Markos, EthiopiaDepartment of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Science, Wollo University, Dessie, EthiopiaDepartment of Public Health, College of Medicine and Health Science, Debre Markos University, Debre Markos, EthiopiaIntroductionAnxiety and depression are among the common comorbidities of people diagnosed with cancer. However, despite the progress in therapeutic options and outcomes, mental health care and support have lagged behind for cancer patients. Estimating the extent and determinants of mental health disorders among cancer patients is crucial to alert concerned bodies for action. In view of this, we aimed to determine the pooled prevalence and determinants of anxiety and depression among cancer patients in Ethiopia.MethodsRelevant literatures were searched on PubMed, African Journals Online, Hinari, Epistemonikos, Scopus, EMBASE, CINAHL, Cochrane Library, and Gray literature sources. Data were extracted into an Excel spreadsheet and analyzed using STATA 17 statistical software. The random effect model was used to summarize the pooled effect sizes with their respective 95% confidence intervals. The I2 statistics and Egger’s regression test in conjunction with the funnel plot were utilized to evaluate heterogeneity and publication bias among included studies respectively.ResultsA total of 17 studies with 5,592 participants were considered in this review. The pooled prevalence of anxiety and depression among cancer patients in Ethiopia were 45.10% (95% CI: 36.74, 53.45) and 42.96% (95% CI: 34.98, 50.93), respectively. Primary and above education (OR= 0.76, 95% CI: 0.60, 0.97), poor social support (OR= 2.27, 95% CI: 1.29, 3.98), occupational status (OR= 0.59; 95% CI: 0.43, 0.82), advanced cancer stage (OR= 2.19, 95% CI: 1.38, 3.47), comorbid illness (OR= 1.67; 95% CI: 1.09, 2.58) and poor sleep quality (OR= 11.34, 95% CI: 6.47, 19.89) were significantly associated with depression. Whereas, advanced cancer stage (OR= 1.59, 95% CI: 1.15, 2.20) and poor sleep quality (OR= 12.56, 95% CI: 6.4 1, 24.62) were the factors associated with anxiety.ConclusionThis meta-analysis indicated that a substantial proportion of cancer patients suffer from anxiety and depression in Ethiopia. Educational status, occupational status, social support, cancer stage, comorbid illness and sleep quality were significantly associated with depression. Whereas, anxiety was predicted by cancer stage and sleep quality. Thus, the provision of comprehensive mental health support as a constituent of chronic cancer care is crucial to mitigate the impact and occurrence of anxiety and depression among cancer patients. Besides, families and the community should strengthen social support for cancer patients.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42023468621.https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1341448/fullanxietydepressionprevalencecancer patientsEthiopia |
| spellingShingle | Habtamu Geremew Samuel Abdisa Elyas Melaku Mazengia Werkneh Melkie Tilahun Aysheshim Belaineh Haimanot Tigabu Kidie Tesfie Anteneh Lamesgen Mneneh Muluye Gebrie Mengie Bekalu Endalew Molla Yigzaw Birhanu Lakew Asmare Mulat Belay Simegn Anxiety and depression among cancer patients in Ethiopia: a systematic review and meta-analysis Frontiers in Psychiatry anxiety depression prevalence cancer patients Ethiopia |
| title | Anxiety and depression among cancer patients in Ethiopia: a systematic review and meta-analysis |
| title_full | Anxiety and depression among cancer patients in Ethiopia: a systematic review and meta-analysis |
| title_fullStr | Anxiety and depression among cancer patients in Ethiopia: a systematic review and meta-analysis |
| title_full_unstemmed | Anxiety and depression among cancer patients in Ethiopia: a systematic review and meta-analysis |
| title_short | Anxiety and depression among cancer patients in Ethiopia: a systematic review and meta-analysis |
| title_sort | anxiety and depression among cancer patients in ethiopia a systematic review and meta analysis |
| topic | anxiety depression prevalence cancer patients Ethiopia |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1341448/full |
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