A cross sectional study of HPV type prevalence according to age and cytology
<p>Abstract</p> <p>Background</p> <p>A cross sectional study to investigate HPV prevalence according to age and cytology.</p> <p>Methods</p> <p>Women presenting to a gynaecological outpatient clinic for a Pap smear test were included in the study...
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| Language: | English |
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BMC
2013-01-01
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| Series: | BMC Infectious Diseases |
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| Online Access: | http://www.biomedcentral.com/1471-2334/13/53 |
| _version_ | 1818859101024681984 |
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| author | Argyri Elena Papaspyridakos Stefanos Tsimplaki Elpida Michala Lina Myriokefalitaki Evangelia Papassideri Issidora Daskalopoulou Dimitra Tsiaoussi Ioanna Magiakos George Panotopoulou Efstathia |
| author_facet | Argyri Elena Papaspyridakos Stefanos Tsimplaki Elpida Michala Lina Myriokefalitaki Evangelia Papassideri Issidora Daskalopoulou Dimitra Tsiaoussi Ioanna Magiakos George Panotopoulou Efstathia |
| author_sort | Argyri Elena |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>A cross sectional study to investigate HPV prevalence according to age and cytology.</p> <p>Methods</p> <p>Women presenting to a gynaecological outpatient clinic for a Pap smear test were included in the study (n=3177). All women had cervical cytology and HPV testing.</p> <p>Results</p> <p>Overall prevalence of any 24 HPV type analysed was 33.1% (95% CI 31.5% to 34.7%) and HPV 16 and HPV 42 were the most frequent (6.7% (95% CI 5.8% to 7.6%), 6.8% (95% CI 5.9% to 7.6%)), in total samples. Multiple HPV infection rate was 12.9% (95% CI 11.8% to 14.1%). High risk HPV (hrHPV) types were present in 27.4% (95% CI 25.8% to 28.9%) of the samples.</p> <p>HPV prevalence was highest among 14 to 19 y.o (46.6% (95% CI 40.7%-52.4%)) and second highest among 30–34 y.o. (39.7%, 95% CI 35.4%–44%). HPV 16 was highest among 20–24 (9.0% (95% CI 6.4%–11.6%)) and second highest among 50 to 54 y.o. (6.3% (95% CI 2.9% to 9.8%).</p> <p>In Low-grade Squamous Intraepithelial Lesions (LgSIL) cytology samples, the most frequently detected hrHPV types were: 16 (14.5% (95% CI 12.1% to 16.9%)), 51 (13.0% (95% CI 10.7% to 15.3%)) and 53 (9.1% (95% CI 7.2% to 11.1%)) and in High-grade Squamous Intraepithelial Lesions (HgSIL) were: HPV 16 (37.2% (95% CI 26.5% to 47.9%)), HPV 51 (17.9% (95% CI 9.4% to 26.5%)) and HPV 18 (12.8% (95% CI 5.4% to 20.2%)).</p> <p>Conclusions</p> <p>In the population studied, HPV 16 and 51 were the most frequent detected hrHPV types. HPV positivity, hrHPV and multiple HPV types infections were higher in young women, while HPV prevalence declined with increasing age and presented two peaks a higher (14–19 y.o.) and a lower one (30–34 y.o.) These results may contribute to the creation of a national screening programme.</p> |
| first_indexed | 2024-12-19T09:06:49Z |
| format | Article |
| id | doaj.art-2a29e64b3af24b3fa7f47c9828ec1a36 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-19T09:06:49Z |
| publishDate | 2013-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-2a29e64b3af24b3fa7f47c9828ec1a362022-12-21T20:28:19ZengBMCBMC Infectious Diseases1471-23342013-01-011315310.1186/1471-2334-13-53A cross sectional study of HPV type prevalence according to age and cytologyArgyri ElenaPapaspyridakos StefanosTsimplaki ElpidaMichala LinaMyriokefalitaki EvangeliaPapassideri IssidoraDaskalopoulou DimitraTsiaoussi IoannaMagiakos GeorgePanotopoulou Efstathia<p>Abstract</p> <p>Background</p> <p>A cross sectional study to investigate HPV prevalence according to age and cytology.</p> <p>Methods</p> <p>Women presenting to a gynaecological outpatient clinic for a Pap smear test were included in the study (n=3177). All women had cervical cytology and HPV testing.</p> <p>Results</p> <p>Overall prevalence of any 24 HPV type analysed was 33.1% (95% CI 31.5% to 34.7%) and HPV 16 and HPV 42 were the most frequent (6.7% (95% CI 5.8% to 7.6%), 6.8% (95% CI 5.9% to 7.6%)), in total samples. Multiple HPV infection rate was 12.9% (95% CI 11.8% to 14.1%). High risk HPV (hrHPV) types were present in 27.4% (95% CI 25.8% to 28.9%) of the samples.</p> <p>HPV prevalence was highest among 14 to 19 y.o (46.6% (95% CI 40.7%-52.4%)) and second highest among 30–34 y.o. (39.7%, 95% CI 35.4%–44%). HPV 16 was highest among 20–24 (9.0% (95% CI 6.4%–11.6%)) and second highest among 50 to 54 y.o. (6.3% (95% CI 2.9% to 9.8%).</p> <p>In Low-grade Squamous Intraepithelial Lesions (LgSIL) cytology samples, the most frequently detected hrHPV types were: 16 (14.5% (95% CI 12.1% to 16.9%)), 51 (13.0% (95% CI 10.7% to 15.3%)) and 53 (9.1% (95% CI 7.2% to 11.1%)) and in High-grade Squamous Intraepithelial Lesions (HgSIL) were: HPV 16 (37.2% (95% CI 26.5% to 47.9%)), HPV 51 (17.9% (95% CI 9.4% to 26.5%)) and HPV 18 (12.8% (95% CI 5.4% to 20.2%)).</p> <p>Conclusions</p> <p>In the population studied, HPV 16 and 51 were the most frequent detected hrHPV types. HPV positivity, hrHPV and multiple HPV types infections were higher in young women, while HPV prevalence declined with increasing age and presented two peaks a higher (14–19 y.o.) and a lower one (30–34 y.o.) These results may contribute to the creation of a national screening programme.</p>http://www.biomedcentral.com/1471-2334/13/53Human papillomavirus (HPV)PrevalenceTypingAge-distributionCytology |
| spellingShingle | Argyri Elena Papaspyridakos Stefanos Tsimplaki Elpida Michala Lina Myriokefalitaki Evangelia Papassideri Issidora Daskalopoulou Dimitra Tsiaoussi Ioanna Magiakos George Panotopoulou Efstathia A cross sectional study of HPV type prevalence according to age and cytology BMC Infectious Diseases Human papillomavirus (HPV) Prevalence Typing Age-distribution Cytology |
| title | A cross sectional study of HPV type prevalence according to age and cytology |
| title_full | A cross sectional study of HPV type prevalence according to age and cytology |
| title_fullStr | A cross sectional study of HPV type prevalence according to age and cytology |
| title_full_unstemmed | A cross sectional study of HPV type prevalence according to age and cytology |
| title_short | A cross sectional study of HPV type prevalence according to age and cytology |
| title_sort | cross sectional study of hpv type prevalence according to age and cytology |
| topic | Human papillomavirus (HPV) Prevalence Typing Age-distribution Cytology |
| url | http://www.biomedcentral.com/1471-2334/13/53 |
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