P2X4 receptor modulates gut inflammation and favours microbial homeostasis in colitis

P2X4 receptor modulates gut inflammation and favours microbial homeostasis in colitis

Abstract Background Inflammatory bowel disease (IBD) is a non‐specific chronic inflammatory disease of the intestine. In addition to genetic susceptibility, environmental factors and dysregulated host immunity, the gut microbiota is implicated in the pathogenesis of Crohn's disease (CD) or ulce...

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Bibliographic Details
Main Authors: Peijie Zhong, Hang Wu, Yuanqiao Ma, Xiaoxiao Xu, Yizhuo Jiang, Chaolei Jin, Qiaozhen Zhu, Xinlei Liu, Zhimin Suo, Junpeng Wang
Format: Article
Language:English
Published: Wiley 2023-04-01
Series:Clinical and Translational Medicine
Subjects:
gut microbiota
gut permeability
inflammatory bowel diseases
P2X4 receptor
Online Access:https://doi.org/10.1002/ctm2.1227

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