Study of Alcohol Extract of Sesame on Wound Healing of Diabetic Male Wistar Rats

Introduction and Aims Diabetes is a metabolic disorder, which is characterized by hyperglycemia resulting from defects in insulin secretion and impaired pancreatic function. Regarding to the medicinal properties of amaranth, this study was conducted to investigate the effects of amaranth on skin his...

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Main Authors: Mitra Bagheri, Sahar Molzemi, Mahbobeh Hadizadeh, Mohsen Aminian
Format: Article
Language:fas
Published: Neyshabur University of Medical Sciences 2016-02-01
Series:Majallah-i Dānishkadah-i ̒ulūm-i Pizishkī-i Niyshābūr
Subjects:
Online Access:http://journal.nums.ac.ir/browse.php?a_code=A-10-1-70&slc_lang=en&sid=1
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author Mitra Bagheri
Sahar Molzemi
Mahbobeh Hadizadeh
Mohsen Aminian
author_facet Mitra Bagheri
Sahar Molzemi
Mahbobeh Hadizadeh
Mohsen Aminian
author_sort Mitra Bagheri
collection DOAJ
description Introduction and Aims Diabetes is a metabolic disorder, which is characterized by hyperglycemia resulting from defects in insulin secretion and impaired pancreatic function. Regarding to the medicinal properties of amaranth, this study was conducted to investigate the effects of amaranth on skin histomorphological changes in diabetic rats. Materials and Methods In this study, 48 male Wistar rats were divided into four groups (control group, sham group, first experimental group, and second experimental group). In these rats, an injured area of 3cm2 was created on the left spine. Wound healing was evaluated macroscopically. Results Wound healing in group that became diabetes using streptozocin, showed late recovery compared to normal wound healing in normal groups and wound healing in experimental groups treated with alcohol extract of sesame was accelerated compared to control group. Conclusion Results of this study showed that alcohol extract of sesame causes accelerated skin wound healing in normal and diabetic samples. * Corresponding Author: Islamic Azad University, Shahrood Branch, School of Medical Sciences. Email: Saharmolzemi@yahoo.com
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spelling doaj.art-2a2bda15567548c88f3f46fabc3d9de52022-12-22T03:24:38ZfasNeyshabur University of Medical SciencesMajallah-i Dānishkadah-i ̒ulūm-i Pizishkī-i Niyshābūr2383-32032476-27682016-02-013419Study of Alcohol Extract of Sesame on Wound Healing of Diabetic Male Wistar RatsMitra Bagheri0Sahar Molzemi1Mahbobeh Hadizadeh2Mohsen Aminian3 Introduction and Aims Diabetes is a metabolic disorder, which is characterized by hyperglycemia resulting from defects in insulin secretion and impaired pancreatic function. Regarding to the medicinal properties of amaranth, this study was conducted to investigate the effects of amaranth on skin histomorphological changes in diabetic rats. Materials and Methods In this study, 48 male Wistar rats were divided into four groups (control group, sham group, first experimental group, and second experimental group). In these rats, an injured area of 3cm2 was created on the left spine. Wound healing was evaluated macroscopically. Results Wound healing in group that became diabetes using streptozocin, showed late recovery compared to normal wound healing in normal groups and wound healing in experimental groups treated with alcohol extract of sesame was accelerated compared to control group. Conclusion Results of this study showed that alcohol extract of sesame causes accelerated skin wound healing in normal and diabetic samples. * Corresponding Author: Islamic Azad University, Shahrood Branch, School of Medical Sciences. Email: Saharmolzemi@yahoo.comhttp://journal.nums.ac.ir/browse.php?a_code=A-10-1-70&slc_lang=en&sid=1wound healing extract sesame rats diabetes
spellingShingle Mitra Bagheri
Sahar Molzemi
Mahbobeh Hadizadeh
Mohsen Aminian
Study of Alcohol Extract of Sesame on Wound Healing of Diabetic Male Wistar Rats
Majallah-i Dānishkadah-i ̒ulūm-i Pizishkī-i Niyshābūr
wound healing
extract
sesame
rats
diabetes
title Study of Alcohol Extract of Sesame on Wound Healing of Diabetic Male Wistar Rats
title_full Study of Alcohol Extract of Sesame on Wound Healing of Diabetic Male Wistar Rats
title_fullStr Study of Alcohol Extract of Sesame on Wound Healing of Diabetic Male Wistar Rats
title_full_unstemmed Study of Alcohol Extract of Sesame on Wound Healing of Diabetic Male Wistar Rats
title_short Study of Alcohol Extract of Sesame on Wound Healing of Diabetic Male Wistar Rats
title_sort study of alcohol extract of sesame on wound healing of diabetic male wistar rats
topic wound healing
extract
sesame
rats
diabetes
url http://journal.nums.ac.ir/browse.php?a_code=A-10-1-70&slc_lang=en&sid=1
work_keys_str_mv AT mitrabagheri studyofalcoholextractofsesameonwoundhealingofdiabeticmalewistarrats
AT saharmolzemi studyofalcoholextractofsesameonwoundhealingofdiabeticmalewistarrats
AT mahbobehhadizadeh studyofalcoholextractofsesameonwoundhealingofdiabeticmalewistarrats
AT mohsenaminian studyofalcoholextractofsesameonwoundhealingofdiabeticmalewistarrats