The Effects of The Artificial Tears Preparations on Contrast Sensitivity in Healthy Individuals
Aim: Determination of the change in contrast sensitivity (CS) values according to time after the use of artificial tears preparations with a different retention time (RT) and different viscosity in healthy individuals. Methods: From 120 healthy individuals, after a detailed ophthalmologic examinatio...
| Main Author: | |
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| Format: | Article |
| Language: | English |
| Published: |
Alanya Alaaddin Keykubat University
2019-08-01
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| Series: | Acta Medica Alanya |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/en/pub/medalanya/issue/48174/533985?publisher=alku |
| _version_ | 1797917169042849792 |
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| author | Mehmet Fatih Küçük |
| author_facet | Mehmet Fatih Küçük |
| author_sort | Mehmet Fatih Küçük |
| collection | DOAJ |
| description | Aim: Determination of the change in contrast sensitivity (CS) values according to time after the use of artificial tears preparations with a different retention time (RT) and different viscosity in healthy individuals. Methods: From 120 healthy individuals, after a detailed
ophthalmologic examination, fifteen were included in the study. Low viscosity
Hydroxypropyl methylcellulose (HPMC)+Dextran 70 (Drug A), low viscosity
Polyvinyl prolidone (Drug B) and high viscosity Polyacrylic acid gel (Drug C)
artificial tears preparations were used. First Drug A was used, followed one
week later by Drug B, and lastly by Drug C. One eye of the individuals were selected
randomly and one drop was added after 1-5, 15, 30, 60, 90 minutes; CS values
were measured with Functional Acuity Contrast Test (FACT).
Results:
With Drug A, at 6 cycles per degree (cpd) spatial frequency, the values
of CS at 30th,60th,90th min. significantly increased compared to the values at
base (0 min) and 1st-5th min. (p<0,05). With Drug B, at 12 cpd
frequency, the values at 30th min. significantly increased, compared to the
values at 1st-5th min.
(p<0.05). With medication C, at 3 cpd frequency, the values at 1st-5th min.
significantly decreased, compared to the values at base (0th min.), 15th, 30th ,60th
,90th min. (p<0,05). With C, at 6 cpd frequency, the values at
1st-5th min. significantly decreased compared to the values at base (0th
minute), 30th, 60th ,90th min. (p<0,01). Also at 15th min., we
noted a significant decrease in the values compared to values at 30th, 90th
min. (p<0,05). Again with C at 12 cpd frequency, the values at 1st-5th min.
significantly decreased compared to values at base (0th min), 60th, 90th
min. (p<0,05).
Conclusion: In the case of healthy individuals with tears film stability problems with the use of low viscosity artificial tears preparation in the form of drops, It could not be shown to decrease retinal image quality by applying CS test within retention times, even increased in some spatial frequencies. |
| first_indexed | 2024-04-10T13:09:00Z |
| format | Article |
| id | doaj.art-2a2c9541891f47e588299b0f56450f62 |
| institution | Directory Open Access Journal |
| issn | 2587-0319 |
| language | English |
| last_indexed | 2024-04-10T13:09:00Z |
| publishDate | 2019-08-01 |
| publisher | Alanya Alaaddin Keykubat University |
| record_format | Article |
| series | Acta Medica Alanya |
| spelling | doaj.art-2a2c9541891f47e588299b0f56450f622023-02-15T16:12:42ZengAlanya Alaaddin Keykubat UniversityActa Medica Alanya2587-03192019-08-013211612310.30565/medalanya.533985727The Effects of The Artificial Tears Preparations on Contrast Sensitivity in Healthy IndividualsMehmet Fatih Küçük0ALANYA ALAADDIN KEYKUBAT UNIVERSITY, FACULTY OF MEDICINEAim: Determination of the change in contrast sensitivity (CS) values according to time after the use of artificial tears preparations with a different retention time (RT) and different viscosity in healthy individuals. Methods: From 120 healthy individuals, after a detailed ophthalmologic examination, fifteen were included in the study. Low viscosity Hydroxypropyl methylcellulose (HPMC)+Dextran 70 (Drug A), low viscosity Polyvinyl prolidone (Drug B) and high viscosity Polyacrylic acid gel (Drug C) artificial tears preparations were used. First Drug A was used, followed one week later by Drug B, and lastly by Drug C. One eye of the individuals were selected randomly and one drop was added after 1-5, 15, 30, 60, 90 minutes; CS values were measured with Functional Acuity Contrast Test (FACT). Results: With Drug A, at 6 cycles per degree (cpd) spatial frequency, the values of CS at 30th,60th,90th min. significantly increased compared to the values at base (0 min) and 1st-5th min. (p<0,05). With Drug B, at 12 cpd frequency, the values at 30th min. significantly increased, compared to the values at 1st-5th min. (p<0.05). With medication C, at 3 cpd frequency, the values at 1st-5th min. significantly decreased, compared to the values at base (0th min.), 15th, 30th ,60th ,90th min. (p<0,05). With C, at 6 cpd frequency, the values at 1st-5th min. significantly decreased compared to the values at base (0th minute), 30th, 60th ,90th min. (p<0,01). Also at 15th min., we noted a significant decrease in the values compared to values at 30th, 90th min. (p<0,05). Again with C at 12 cpd frequency, the values at 1st-5th min. significantly decreased compared to values at base (0th min), 60th, 90th min. (p<0,05). Conclusion: In the case of healthy individuals with tears film stability problems with the use of low viscosity artificial tears preparation in the form of drops, It could not be shown to decrease retinal image quality by applying CS test within retention times, even increased in some spatial frequencies.https://dergipark.org.tr/en/pub/medalanya/issue/48174/533985?publisher=alkusuni gözyaşı preparatıkontrast duyarlılıkkalıcılık süresiviskoziteartificial tears preparationscontrast sensitivityretention timeviscosity |
| spellingShingle | Mehmet Fatih Küçük The Effects of The Artificial Tears Preparations on Contrast Sensitivity in Healthy Individuals Acta Medica Alanya suni gözyaşı preparatı kontrast duyarlılık kalıcılık süresi viskozite artificial tears preparations contrast sensitivity retention time viscosity |
| title | The Effects of The Artificial Tears Preparations on Contrast Sensitivity in Healthy Individuals |
| title_full | The Effects of The Artificial Tears Preparations on Contrast Sensitivity in Healthy Individuals |
| title_fullStr | The Effects of The Artificial Tears Preparations on Contrast Sensitivity in Healthy Individuals |
| title_full_unstemmed | The Effects of The Artificial Tears Preparations on Contrast Sensitivity in Healthy Individuals |
| title_short | The Effects of The Artificial Tears Preparations on Contrast Sensitivity in Healthy Individuals |
| title_sort | effects of the artificial tears preparations on contrast sensitivity in healthy individuals |
| topic | suni gözyaşı preparatı kontrast duyarlılık kalıcılık süresi viskozite artificial tears preparations contrast sensitivity retention time viscosity |
| url | https://dergipark.org.tr/en/pub/medalanya/issue/48174/533985?publisher=alku |
| work_keys_str_mv | AT mehmetfatihkucuk theeffectsoftheartificialtearspreparationsoncontrastsensitivityinhealthyindividuals AT mehmetfatihkucuk effectsoftheartificialtearspreparationsoncontrastsensitivityinhealthyindividuals |