The Requirement of Sox2 for the Spinal Cord Motor Neuron Development of Zebrafish

The Requirement of Sox2 for the Spinal Cord Motor Neuron Development of Zebrafish

Sex-determining region Y box 2 (Sox2), expressed in neural tissues, plays an important role as a transcription factor not only in the pluripotency and proliferation of neuronal cells but also in the opposite function of cell differentiation. Nevertheless, how Sox2 is linked to motor neuron developme...

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Bibliographic Details
Main Authors: Jie Gong, Songqun Hu, Zigang Huang, Yuebo Hu, Xiaoning Wang, Jinxiang Zhao, Peipei Qian, Cheng Wang, Jiajing Sheng, Xiaofeng Lu, Guanyun Wei, Dong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Sox2
motor neuron
axons
zebrafish
differentiation
development
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2020.00034/full

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