Palmitic Acid Inhibits the Growth and Metastasis of Gastric Cancer by Blocking the STAT3 Signaling Pathway
Lipidomic analyses have suggested that palmitic acid (PA) is linked to gastric cancer. However, its effects and action mechanisms remain unclear. Therefore, we evaluated the effects of PA on cell proliferation, invasion, and apoptosis in human gastric cancer, as well as the role of p-STAT3 in mediat...
Main Authors: | Xiaojuan Yu, Wen Peng, Yaoxing Wang, Wenjun Xu, Wentong Chen, Lei Huang, Hu Xu, Xinyu He, Sheng Wang, Qianqian Sun, Wenjie Lu, Youzhi Xu |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-01-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/15/2/388 |
Similar Items
-
Integrated Metabolomics and Lipidomics Reveal High Accumulation of Glycerophospholipids in Human Astrocytes under the Lipotoxic Effect of Palmitic Acid and Tibolone Protection
by: Ricardo Cabezas, et al.
Published: (2022-02-01) -
Phosphatidylserine decarboxylase downregulation in uric acid‑induced hepatic mitochondrial dysfunction and apoptosis
by: Ning Liu, et al.
Published: (2023-08-01) -
Atlas of metabolism reveals palmitic acid results in mitochondrial dysfunction and cell apoptosis by inhibiting fatty acid β-oxidation in Sertoli cells
by: Xiaoqin Xu, et al.
Published: (2022-09-01) -
Role of Metabolomics in Pathogenesis and Prompt Diagnosis of Gastric Cancer Metastasis—A Systematic Review
by: Ștefan Ursu, et al.
Published: (2023-11-01) -
Stat‐3 signaling promotes cell proliferation and metastasis of gastric cancer through PDCD4 downregulation
by: Yue‐Lou Yang, et al.
Published: (2020-04-01)