Verbascoside protects from LPS-induced septic cardiomyopathy via alleviating cardiac inflammation, oxidative stress and regulating mitochondrial dynamics

Verbascoside protects from LPS-induced septic cardiomyopathy via alleviating cardiac inflammation, oxidative stress and regulating mitochondrial dynamics

Background: Verbascoside (VB), as an active component of multiple medicinal plants, has been proved to exert anti-oxidative, anti-aging and neuroprotective effects. This study was designed to investigate whether VB could play a cardioprotective role in septic heart injury. Methods: Mice were injecte...

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Bibliographic Details
Main Authors: Xuanfeng Zhu, Min Sun, Hongmei Guo, Gan Lu, Jianhua Gu, Lingling Zhang, Licheng Shi, Jia Gao, Dandan Zhang, Wenjun Wang, Jiannan Liu, Xia Wang
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Verbascoside
Sepsis-induced cardiomyopathy
Mitochondrial biogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322001671

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