Recent advances in acoustofluidic separation technology in biology
Abstract Acoustofluidic separation of cells and particles is an emerging technology that integrates acoustics and microfluidics. In the last decade, this technology has attracted significant attention due to its biocompatible, contactless, and label-free nature. It has been widely validated in the s...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2022-09-01
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| Series: | Microsystems & Nanoengineering |
| Online Access: | https://doi.org/10.1038/s41378-022-00435-6 |
| _version_ | 1798004419063709696 |
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| author | Yanping Fan Xuan Wang Jiaqi Ren Francis Lin Jiandong Wu |
| author_facet | Yanping Fan Xuan Wang Jiaqi Ren Francis Lin Jiandong Wu |
| author_sort | Yanping Fan |
| collection | DOAJ |
| description | Abstract Acoustofluidic separation of cells and particles is an emerging technology that integrates acoustics and microfluidics. In the last decade, this technology has attracted significant attention due to its biocompatible, contactless, and label-free nature. It has been widely validated in the separation of cells and submicron bioparticles and shows great potential in different biological and biomedical applications. This review first introduces the theories and mechanisms of acoustofluidic separation. Then, various applications of this technology in the separation of biological particles such as cells, viruses, biomolecules, and exosomes are summarized. Finally, we discuss the challenges and future prospects of this field. |
| first_indexed | 2024-04-11T12:24:27Z |
| format | Article |
| id | doaj.art-2a30d9348b7b46f1addc6b42fe9dc4bd |
| institution | Directory Open Access Journal |
| issn | 2055-7434 |
| language | English |
| last_indexed | 2024-04-11T12:24:27Z |
| publishDate | 2022-09-01 |
| publisher | Nature Publishing Group |
| record_format | Article |
| series | Microsystems & Nanoengineering |
| spelling | doaj.art-2a30d9348b7b46f1addc6b42fe9dc4bd2022-12-22T04:24:00ZengNature Publishing GroupMicrosystems & Nanoengineering2055-74342022-09-018111610.1038/s41378-022-00435-6Recent advances in acoustofluidic separation technology in biologyYanping Fan0Xuan Wang1Jiaqi Ren2Francis Lin3Jiandong Wu4School of Optical-Electrical and Computer Engineering, University of Shanghai for Science and TechnologySchool of Optical-Electrical and Computer Engineering, University of Shanghai for Science and TechnologyInstitute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of SciencesDepartment of Physics and Astronomy, University of ManitobaInstitute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of SciencesAbstract Acoustofluidic separation of cells and particles is an emerging technology that integrates acoustics and microfluidics. In the last decade, this technology has attracted significant attention due to its biocompatible, contactless, and label-free nature. It has been widely validated in the separation of cells and submicron bioparticles and shows great potential in different biological and biomedical applications. This review first introduces the theories and mechanisms of acoustofluidic separation. Then, various applications of this technology in the separation of biological particles such as cells, viruses, biomolecules, and exosomes are summarized. Finally, we discuss the challenges and future prospects of this field.https://doi.org/10.1038/s41378-022-00435-6 |
| spellingShingle | Yanping Fan Xuan Wang Jiaqi Ren Francis Lin Jiandong Wu Recent advances in acoustofluidic separation technology in biology Microsystems & Nanoengineering |
| title | Recent advances in acoustofluidic separation technology in biology |
| title_full | Recent advances in acoustofluidic separation technology in biology |
| title_fullStr | Recent advances in acoustofluidic separation technology in biology |
| title_full_unstemmed | Recent advances in acoustofluidic separation technology in biology |
| title_short | Recent advances in acoustofluidic separation technology in biology |
| title_sort | recent advances in acoustofluidic separation technology in biology |
| url | https://doi.org/10.1038/s41378-022-00435-6 |
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