Promoting Neuronal Outgrowth Using Ridged Scaffolds Coated with Extracellular Matrix Proteins

Promoting Neuronal Outgrowth Using Ridged Scaffolds Coated with Extracellular Matrix Proteins

Spinal cord injury (SCI) results in cell death, demyelination, and axonal loss. The spinal cord has a limited ability to regenerate, and current clinical therapies for SCI are not effective in helping promote neurologic recovery. We have developed a novel scaffold biomaterial that is fabricated from...

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Bibliographic Details
Main Authors: Ahad M. Siddiqui, Rosa Brunner, Gregory M. Harris, Alan Lee Miller, Brian E. Waletzki, Ann M. Schmeichel, Jean E. Schwarzbauer, Jeffrey Schwartz, Michael J. Yaszemski, Anthony J. Windebank, Nicolas N. Madigan
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomedicines
Subjects:
neuronal outgrowth
cell attachment
Schwann cells
extracellular matrix
scaffolds
spinal cord
Online Access:https://www.mdpi.com/2227-9059/9/5/479

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