DNA methylation and cis-regulation of gene expression by prostate cancer risk SNPs.

DNA methylation and cis-regulation of gene expression by prostate cancer risk SNPs.

Genome-wide association studies have identified more than 100 SNPs that increase the risk of prostate cancer (PrCa). We identify and compare expression quantitative trait loci (eQTLs) and CpG methylation quantitative trait loci (meQTLs) among 147 established PrCa risk SNPs in primary prostate tumors...

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Bibliographic Details
Main Authors: James Y Dai, Xiaoyu Wang, Bo Wang, Wei Sun, Kristina M Jordahl, Suzanne Kolb, Yaw A Nyame, Jonathan L Wright, Elaine A Ostrander, Ziding Feng, Janet L Stanford
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-03-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008667

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