Cited2 regulates proliferation and survival in young and old mouse cardiac stem cells

Cited2 regulates proliferation and survival in young and old mouse cardiac stem cells

Abstract Background Cardiac stem cells (CSCs) exhibit age-dependent characteristics. Cited2 has been implicated in the regulation of heart development; however, there is little known about how Cited2 affects CSC aging. Results Cited2 mRNA and protein level was downregulated in aging heart tissue and...

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Bibliographic Details
Main Authors: Qiong Wu, Qin Liu, Jinxi Zhan, Qian Wang, Daxiu Zhang, Shuangli He, Shiming Pu, Zuping Zhou
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Molecular and Cell Biology
Subjects:
Cardiac stem cells
Cited2
Aging
Apoptosis
Proliferation
Online Access:http://link.springer.com/article/10.1186/s12860-019-0207-2

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