Rare isolation of human-tropic recombinant porcine endogenous retroviruses PERV-A/C from Göttingen minipigs

Rare isolation of human-tropic recombinant porcine endogenous retroviruses PERV-A/C from Göttingen minipigs

Abstract Background Porcine endogenous retroviruses (PERVs) can infect human cells and pose a risk for xenotransplantation when pig cells, tissues or organs are transplanted to human recipients. Xenotransplantation holds great promise to overcome the shortage of human donor organs after solving the...

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Bibliographic Details
Main Authors: Sabrina Halecker, Ludwig Krabben, Yannick Kristiansen, Luise Krüger, Lars Möller, Dietmar Becher, Michael Laue, Benedikt Kaufer, Christian Reimer, Joachim Denner
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Virology Journal
Subjects:
Xenotransplantation
Porcine endogenous retroviruses
Recombination
Long terminal repeats
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Online Access:https://doi.org/10.1186/s12985-022-01742-0

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