Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells

Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells

Being the largest the Ca<sup>2+</sup> store in mammalian cells, endoplasmic reticulum (ER)-mediated Ca<sup>2+</sup> signalling often involves both Ca<sup>2+</sup> release via inositol 1, 4, 5-trisphosphate receptors (IP<sub>3</sub>R) and store operated...

Full description

Bibliographic Details
Main Authors:	Lili Yue, Liuqing Wang, Yangchun Du, Wei Zhang, Kozo Hamada, Yoshifumi Matsumoto, Xi Jin, Yandong Zhou, Katsuhiko Mikoshiba, Donald L. Gill, Shengcheng Han, Youjun Wang
Format:	Article
Language:	English
Published:	MDPI AG 2020-01-01
Series:	Cells
Subjects:	ip<sub>3</sub>r store-operated ca<sup>2+</sup> entry orai1 serca nedd4l calcium
Online Access:	https://www.mdpi.com/2073-4409/9/2/275

Similar Items

Role of Store-Operated Ca<sup>2+</sup> Entry in the Pulmonary Vascular Remodeling Occurring in Pulmonary Arterial Hypertension
by: Bastien Masson, et al.
Published: (2021-11-01)

Organic Fertilization of Growing Media: Response of N Mineralization to Temperature and Moisture
by: Patrice Cannavo, et al.
Published: (2022-02-01)

Electromagnetic Interference Shielding of 2D Transition Metal Carbide (MXene)/Metal Ion Composites
by: Xuefeng Xia, et al.
Published: (2021-11-01)

Role of the inositol 1,4,5-trisphosphate receptor/Ca<sup>2+</sup>-release channel in autophagy
by: Parys Jan B, et al.
Published: (2012-07-01)

The Role of Ca<sup>2+</sup> Signaling in Aging and Neurodegeneration: Insights from <i>Caenorhabditis elegans</i> Models
by: Javier Alvarez, et al.
Published: (2020-01-01)

Molecular Choreography and Structure of Ca<sup>2+</sup> Release-Activated Ca<sup>2+</sup> (CRAC) and K<sub>Ca2+</sub> Channels and Their Relevance in Disease with Special Focus on Cancer
by: Adéla Tiffner, et al.
Published: (2020-12-01)

Lessons from the Endoplasmic Reticulum Ca<sup>2+</sup> Transporters—A Cancer Connection
by: Xingjian Zhai, et al.
Published: (2020-06-01)

Genome-Wide Identification and Expression Analysis of PkNRT Gene Family in Korean Pine (<i>Pinus koraiensis</i>)
by: Xinyu Zhao, et al.
Published: (2025-01-01)

Microbiology Combined with the Root Metabolome Reveals the Responses of Root Microorganisms to Maize Cultivars under Different Forms of Nitrogen Supply
by: Guan Tian, et al.
Published: (2024-08-01)

Nitrogen Cycle Dynamics Revealed Through δ<sup>18</sup>O-NO<sub>3</sub><sup>−</sup> Analysis in California Groundwater
by: Nate Veale, et al.
Published: (2019-02-01)

Increased Risk for Atrial Alternans in Rabbit Heart Failure: The Role of Ca<sup>2+</sup>/Calmodulin-Dependent Kinase II and Inositol-1,4,5-trisphosphate Signaling
by: Giedrius Kanaporis, et al.
Published: (2023-12-01)

Agonist-Induced Ca<sup>2+</sup> Signaling in HEK-293-Derived Cells Expressing a Single IP<sub>3</sub> Receptor Isoform
by: Ekaterina N. Kochkina, et al.
Published: (2024-03-01)

Highly Selective Adsorption of <sup>99</sup>TcO<sub>4</sub><sup>−</sup>/ReO<sub>4</sub><sup>−</sup> by a Novel Polyamide-Functionalized Polyacrylamide Polymer Material
by: Ben Qin, et al.
Published: (2022-10-01)

What Are the Oxidizing Intermediates in the Fenton and Fenton-like Reactions? A Perspective
by: Dan Meyerstein
Published: (2022-07-01)

Optical Investigation of Eu<sup>3+</sup> Doped Bi<sub>12</sub>GeO<sub>20</sub> (BGO) Crystals
by: M. Kowalczyk, et al.
Published: (2020-04-01)

Enhanced Electrochemical Performance of LiNi<sub>0.5</sub>Mn<sub>1.5</sub>O<sub>4</sub> Composite Cathodes for Lithium-Ion Batteries by Selective Doping of K<sup>+</sup>/Cl<sup>−</sup> and K<sup>+</sup>/F<sup>−</sup>
by: Aijia Wei, et al.
Published: (2021-09-01)

Synergistic Effects of Bicarbonate and Selenium on Cadmium Transport in Karst-Adaptable Plants Based on Plant Electrical Signals
by: Antong Xia, et al.
Published: (2024-01-01)

<sup>7</sup>Be, <sup>210</sup>Pb<sub>atm</sub> and <sup>137</sup>Cs in Snow Deposits in the Arctic Part of Western Siberia (Yamal-Nenets Autonomous District)
by: Kseniya Mezina, et al.
Published: (2020-08-01)

Model Evaluation of the Microbial Metabolic Processes in a Hydrogen-Based Membrane Biofilm Reactor for Simultaneous Bromate and Nitrate Reduction
by: Minmin Jiang, et al.
Published: (2022-08-01)

Preparation of Eu<sub>0.075</sub>Tb<sub>0.925</sub>-Metal Organic Framework as a Fluorescent Probe and Application in the Detection of Fe<sup>3+</sup> and Cr<sub>2</sub>O<sub>7</sub><sup>2−</sup>
by: Jie Yin, et al.
Published: (2021-11-01)

Nitrogen Dynamics in Tropical Soils Treated with Liquid and Granular Urea Fertilizers
by: Ahmmed Md Motasim, et al.
Published: (2021-06-01)

Quantification of Glucose Metabolism and Nitrogen Utilization in Two <i>Brassicaceae</i> Species under Bicarbonate and Variable Ammonium Soil Conditions
by: Antong Xia, et al.
Published: (2023-08-01)

A Ni(II) Coordination Polymer as a Multifunctional Luminescent Sensor for Detection of UO<sub>2</sub><sup>2+</sup>, Cr<sub>2</sub>O<sub>7</sub><sup>2−</sup>, CrO<sub>4</sub><sup>2−</sup> and Nitrofurantoin
by: Yun-Shan Xue, et al.
Published: (2023-06-01)

Prediction and Impact Analysis of Soil Nitrogen and Salinity Under Reclaimed Water Irrigation: A Case Study
by: Zeyu Liu, et al.
Published: (2025-02-01)

Novel Photoinduced Squalene Cyclic Peroxide Identified, Detected, and Quantified in Human Skin Surface Lipids
by: Saoussane Khalifa, et al.
Published: (2021-11-01)

<i>BcAMT1;5</i> Mediates Nitrogen Uptake and Assimilation in Flowering Chinese Cabbage and Improves Plant Growth When Overexpressed in <i>Arabidopsis</i>
by: Yunna Zhu, et al.
Published: (2023-01-01)

Regulation of Ammonium Cellular Levels is An Important Adaptive Trait for the Euhalophytic Behavior of <i>Salicornia europaea</i>
by: Jinbiao Ma, et al.
Published: (2020-02-01)

Assessment of Soil Radioactivity Associated with Risk and Correlation with Soil Properties near Maanshan Nuclear Power Plant, Taiwan
by: Ting-Chien Chen, et al.
Published: (2024-10-01)

Structural Aspects of Pt(η<sup>3</sup>–P<sup>1</sup>C<sub>2</sub>X<sup>1</sup>C<sub>2</sub>P<sup>2</sup>)(Y) Derivative Types
by: Milan Melník, et al.
Published: (2023-09-01)

Biochar–Nitrogen Composites: Synthesis, Properties, and Use as Fertilizer for Maize
by: Caio Pereira Mota, et al.
Published: (2024-04-01)

Resonant Ionic, Covalent Bond, and Steric Characteristics Present in <sup>1</sup>Σ<sub>u</sub><sup>+</sup> States of Li<sub>2</sub>
by: Michiko Ahn Furudate, et al.
Published: (2022-05-01)

A Highly Selective and Sensitive Sequential Recognition Probe Zn<sup>2+</sup> and H<sub>2</sub>PO<sub>4</sub><sup>−</sup> Based on Chiral Thiourea Schiff Base
by: Shan Yang, et al.
Published: (2023-05-01)

H<sub>2</sub>O<sub>2</sub>/Ca<sup>2+</sup>/Zn<sup>2+</sup> Complex Can Be Considered a “Collaborative Sensor” of the Mitochondrial Capacity?
by: Ester Sara Di Filippo, et al.
Published: (2022-02-01)

Physiological and Agronomical Response of Coffee to Different Nitrogen Forms with and without Water Stress
by: Victor Hugo Ramirez-Builes, et al.
Published: (2024-05-01)

Co-Doping Effect of Mn<sup>2+</sup> and Eu<sup>3+</sup> on Luminescence in Strontiowhitlockite Phosphors
by: Ivan V. Nikiforov, et al.
Published: (2023-12-01)

Negative Pressure Irrigation System Reduces Soil Nitrogen Loss for Lettuce during Greenhouse Production
by: Xiang Gao, et al.
Published: (2021-11-01)

Enhanced Photoluminescence of Gd<sub>3</sub>Al<sub>4</sub>GaO<sub>12</sub>: Cr<sup>3+</sup> by Energy Transfers from Co-Doped Dy<sup>3+</sup>
by: Yu Zhang, et al.
Published: (2022-11-01)

Study of the Optical Features of Tb<sup>3+</sup>:CaYAlO<sub>4</sub> and Tb<sup>3+</sup>/Pr<sup>3+</sup>:CaYAlO<sub>4</sub> Crystals for Visible Laser Applications
by: Yeqing Wang, et al.
Published: (2022-11-01)

Influence of Individual Ions on Silica Nanoparticles Interaction with Berea Sandstone Minerals
by: Aly A. Hamouda, et al.
Published: (2019-09-01)

Construction of a Two-Dimensional GO/Ti<sub>3</sub>C<sub>2</sub>T<sub>X</sub> Composite Membrane and Investigation of Mg<sup>2+</sup>/Li<sup>+</sup> Separation Performance
by: Zhenhua Feng, et al.
Published: (2023-10-01)