Alprostadil attenuates myocardial ischemia/reperfusion injury by promoting antioxidant activity and eNOS activation in rats

Alprostadil attenuates myocardial ischemia/reperfusion injury by promoting antioxidant activity and eNOS activation in rats

Abstract Purpose: To investigate the effect of alprostadil on myocardial ischemia/reperfusion (I/R) in rats. Methods: Rats were subjected to myocardial ischemia for 30 min followed by 24h reperfusion. Alprostadil (4 or 8 μg/kg) was intravenously administered at the time of reperfusion and myocar...

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Bibliographic Details
Main Authors:	Liping Zhang, Ying Zhang, Xiaofeng Yu, Huali Xu, Dayuan Sui, Xuezhong Zhao
Format:	Article
Language:	English
Published:	Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2018-12-01
Series:	Acta Cirúrgica Brasileira
Subjects:	Alprostadil Myocardial ischemia Nitric Oxide Rats
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502018001201067&tlng=en

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