Ribosylation rapidly induces alpha-synuclein to form highly cytotoxic molten globules of advanced glycation end products.

BACKGROUND: Alpha synuclein (alpha-Syn) is the main component of Lewy bodies which are associated with several neurodegenerative diseases such as Parkinson's disease. While the glycation with D-glucose that results in alpha-Syn misfold and aggregation has been studied, the effects of glycation...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Lan Chen, Yan Wei, Xueqing Wang, Rongqiao He
বিন্যাস: প্রবন্ধ
ভাষা:English
প্রকাশিত: Public Library of Science (PLoS) 2010-01-01
মালা:PLoS ONE
অনলাইন ব্যবহার করুন:http://europepmc.org/articles/PMC2816216?pdf=render