Design, Synthesis, and Biological Evaluation of Novel Coumarin Analogs Targeted against SARS-CoV-2

Design, Synthesis, and Biological Evaluation of Novel Coumarin Analogs Targeted against SARS-CoV-2

SARS-CoV, an RNA virus, is contagious and displays a remarkable degree of adaptability, resulting in intricate disease presentations marked by frequent genetic mutations that can ultimately give rise to drug resistance. Targeting its viral replication cycle could be a potential therapeutic option to...

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Bibliographic Details
Main Authors: Kirti Sharma, Manjinder Singh, Pratibha Sharma, Sumesh C. Sharma, Somdutt Mujwar, Mohit Kapoor, Krishna Kumar Mishra, Tanveer A. Wani
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Molecules
Subjects:
SARS-CoV-2
M<sup>Pro</sup>
nsP3
scaffold morphing
molecular docking
Online Access:https://www.mdpi.com/1420-3049/29/6/1406

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