MiR-506 Targets UHRF1 to Inhibit Colorectal Cancer Proliferation and Invasion via the KISS1/PI3K/NF-κB Signaling Axis

MiR-506 Targets UHRF1 to Inhibit Colorectal Cancer Proliferation and Invasion via the KISS1/PI3K/NF-κB Signaling Axis

BackgroundThe UHRF1 gene is an epigenetic modification factor that mediates tumor suppressor gene silencing in a variety of cancers. Related studies have reported that UHRF1 can inhibit the expression of the KISS1 gene. However, the regulatory mechanism underlying UHRF1 expression in colorectal canc...

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Bibliographic Details
Main Authors: Yilin Lin, Zhihua Chen, Yan Zheng, Yisu Liu, Ji Gao, Suyong Lin, Shaoqin Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
CRC
miR-506
UHRF1
proliferation
invasion
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00266/full

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